PROMPT SEPSIS : Partnership for Rapid On-site Microfluidic POC Test for Sepsis

利物浦大学（UoL）已经确定了3种生物标志物的组合，可以很好地区分发热儿童的败血症。MicroLab Devices (MLD), Forsite Diagnostics （FD）和UoL结合他们的技术开发了一种创新的护理点（POC）诊断系统，结合了微流体和横向流动技术，为测量这种脓毒症标志物的组合提供了一次性的零能量平台。该项目将完善POC系统，将原始唾液或血液样本直接引入系统，并使用临床样本验证设备，以创建诊断算法来指导决策。创新之处在于生物标志物和平台技术的新组合，提供了一种新的诊断系统，可以快速、廉价地检测败血症。该测试有可能减少诊断延误和不必要的住院，该平台有可能影响整个POC市场。

The University of Liverpool (UoL) has identified a combination of 3 biomarkers which provide good discrimination of sepsisin febrile children. MicroLab Devices (MLD), Forsite Diagnostics (FD) and UoL have combined their technology to developan innovative point-of-care (POC) diagnostic system combining microfluidic and lateral flow technology to provide adisposable, zero energy platform for measuring this combination of sepsis markers. The project will refine the POC systemfor the introduction of raw saliva or blood samples directly into the system and validate the device using clinical samples tocreate a diagnostic algorithm to guide decision making. The innovation lies in the novel combination of biomarkers AND thecombined platform technologies that provide a new diagnostic system to allow the detection of sepsis rapidly and cheaply.The test has the potential to reduce delays in diagnosis and unnecessary admissions to hospital and the platform has thepotential to impact across the whole POC market.