PLASMA SKIMMING OF BLOOD IN BIFURCATIONS IN SERIES

所提出的研究攻击血管中血浆撇除的问题， 用两个分叉的体外复制品进行实验的网络 用红细胞灌注的网络（分支直径10至50 μ m） 暂停。 红细胞速度和红细胞通量的测量可以是 通过Sorelius和Duling的荧光标记技术完成 （1982年）。 氟离子和红细胞流量的测量将 从来自网络复制品的每个分支的流出物的收集。 这项工作的数据和分析将有助于体内微循环学家 解释他们的网络血流结果。 获得的数据 适用于血液流动调节和02的生理问题 交付. 更现实的计算机网络模型可以从 预期数据。 计算机模型的价值在于模拟 他们可以进行的实验，不能在体内进行，在血管中， 疾病研究。 这些类型的模拟实验具有应用性 在高血压和糖尿病中。

The proposed research attacks the problem of plasma skimming in vascular networks with experiments using in vitro replicas of two bifurcation networks (branch diameter 10 to 50 Mum) perfused with red cell suspensions. Measurements of red cell velocity and red cell flux can be accomplished by the fluorescent labelling technique of Sorelius and Duling (1982). Measurements of volumetric fluorates and red cell flux will come from collection of effuent from each branch of the network replica. The data and analysis from this work will help in vivo microcirulationists interpret their results on network blood flow. The data obtained is applicable to the physiological problems of blood flow regulation and 02 delivery. More realistic computer network models can be developed from the anticipated data. The value of computer models is the simulation experiments they can perform, which cannot be done in vivo, in vascular disease research. These types of simulation experiments have application in hypertension and diabetes.