THRESHOLD DETERMINATION WITH AUDITORY BRAINSTEM RESPONSE

该项目的长期目标是提高准确性， 听性脑干反应（ARB）在预测听觉 听障婴儿和幼儿的听阈。 这将是 通过确定最佳刺激和记录参数来完成 用于ABR测听。 一种被称为Fsp的客观技术， 评估所记录的听觉神经电位相对强度 将被用来作为衡量的影响， 记录和刺激操作。 受试者将从两个类别中选择：1.听障成人 2.婴儿。 成年受试者将进一步分为听力损失 将根据严重程度和听力图配置以及婴儿进行分组 根据年龄分为几类。 将评估两种类型的刺激：1。点击2.突然响起的声音 缺口噪声 将操纵以下实验参数：1.记录 滤波器带通电极放置3.刺激率4.刺激 极性 选择每个实验的刺激水平来评估一个范围 在预期阈值之上和之下的反应。 在所有情况下， 将对10，000次扫描进行平均，以优化信噪比， 录音 记录带通效应对ABR阈值的影响 首先评估和产生显着改善的带通 在ABR信噪比将用于后续的实验。 将从三个正交电极进行同步记录 通道和第四个标准临床通道，用于评估电极 放置效果，同时刺激率和极性被操纵。 的 所有实验中的因变量将是相关的Fsp值 每一个回答。 也可以使用Fsp（按刺激水平）功能 以确定任何给定参数集的ARB阈值。 实验的目的是评估刺激和记录效果 以及实验参数之间的相互作用， 听觉障碍与发育的刺激类型和主观因素 阶段

The long-term goal of this project is to increase the accuracy and efficiency of the Auditory Brainstem Response (ARB) in predicting auditory thresholds in hearing-impaired infants and young children. This will be accomplished by determining the optimal stimulus and recording parameters to use for ABR audiometry. An objective technique known as Fsp' which evaluates the strength of the recorded auditory neural potential relative to the background noise will be used as a measure of the effects of recording and stimulus manipulations. Subjects will be selected from two categories: 1. Hearing-impaired adults 2. Infants. Adult subjects will be further divided into hearing-loss groups based on severity and audiogram configuration and infants will be grouped into categories based on age. Two types of stimuli will be evaluated: 1. Clicks 2. Tone bursts in notched noise. The following experimental parameters will be manipulated: 1. Recording filter bandpass 2. Electrode placement 3. Stimulus rate 4. Stimulus polarity. Stimulus levels for each experiment have been chosen to evaluate a range of responses just above and below expected threshold. In all cases, 10,000 sweeps will be averaged to optimize the signal-to-noise ratio of the recordings. Recording bandpass effects on ABR threshold will be evaluated first and the bandpass which produces a significant improvement in the ABR signal-to-noise ratio will be used in subsequent experiments. Simultaneous recordings will be made from three, orthogonal electrode channels and a forth standard clinical channel to evaluate electrode placement effects while stimulus rate and polarity are manipulated. The dependant variable in all experiments will be the Fsp value associated with each response. The Fsp by stimulus level functions can also be used to determine the threshold of the ARB for any given set of parameters. Experiments are designed to evaluate stimulus and recording effects individually as well as interactions between experimental parameters, stimulus type and subject factors of hearing impairment and developmental stage.