SEGMENTAL PULSATILE PRESSURE CUFF/ANALYZER DEVELOPMENT

拟议的研究将开发一个准确的节段性脉动压力 (SPP)用于检测阴茎血流的分析器和阴茎节段袖带 和压力脉冲。 目标是构建两个原型用于研究 以及评估男性阳痿 博士卡拉坎以前对男性阳痿的研究表明， 该装置可用于检测和评估阴茎血液脉冲。 他的工作 已经表明这样的套囊一定不会导致阴茎的物理畸形 在评估过程中，分析仪应准确并能够 维持袖带充气压力12小时，不超过5% 下垂。 早期的调查是用一种专门开发的袖带进行的 用于检测四肢动脉阻塞;仪器（脉搏容积 记录器，由Life Science，Inc.制造）可以保持袖带充气 压力只有30分钟。 Dr. Kazanli修改了那个仪器， 具体应用并提供了工程咨询和二 本申请中引用的原型。 临床应用将包括 评价正常和高血压男性的勃起血流动力学。 博士美国医疗电子公司将授权德州医疗电子公司使用美国专利 #4，279，155（波登管传感器），用于开发两个分析仪 原型

The proposed study will develop an accurate segmental pulsatile pressure (SPP) analyzer and penile segmental cuff for detecting penile blood flow and pressure pulses. The goal is to construct two prototypes for studying and evaluating male impotence. Dr. Karacan's previous work on male impotence has shown that the proposed device could be used to detect and evaluate penile blood pulses. His work has shown that such a cuff must not cause physical deformity of penis during evaluation, and that the analyzer should be accurate and capable of maintaining cuff inflation pressure for 12 hours with no more than 5% droop. Early investigations were conducted with a cuff specially developed for detecting arterial blockage in limbs; the instrument (Pulse Volume Recorder, manufactured by Life Science, Inc.) could maintain cuff inflation pressure for only 30 minutes. Dr. Balkanli modified that instrument for the specific application and provided engineering consultation and two prototypes cited in this application. Clinical application will consist of evaluation erectile hemodynamics in normal and hypertensive males. Dr. Balkanli will license Texas Medical Electronics Co. to use U.S. Patent #4,279,155 (a bourdon tube transducer) for developing the two analyzer prototypes.