MOLECULAR DYNAMICS PHOSPHORIMAGING SYSTEM

该提案是一项协调努力，以满足 大约有150名研究人员从事分子生物学研究， 生物学或蛋白质化学，并需要灵敏，快速定量 分析依赖于检测放射性信号的技术。 这一请求得到了由60名调查员组成的主要用户组的支持 谁会使用这些工具。适当的体制支持， 已承诺为技术顾问，放置的文书， 两个网站，这将是方便所有教师谁将使用 仪器，提供购买外围数据的辅助资金 处理工作站和软件，以及联网 仪器到外围计算机，用于场外数据存储 和操纵仪器的保养和维护计划， 合理使用的时间安排，以及未获得资金的初级 调查人员，已经提供。这些文书将被视为 大学的分子资源核心的一部分，并将管理 由乔治亚伯拉罕博士领导的咨询委员会， 研究副院长和医学教授，芭芭拉博士 Iglewski教授，微生物学和免疫学主席，博士。 Martin Gorovksy，生物学教授兼主席，Fred谢尔曼博士， 教授和生物化学主席，和博士特里普拉特，教授 生物化学。将这些仪器添加到分子生物学 在大学和医学院的设施将是非常有益的， 调查人员，将显着减少需要和浪费， 放射性化学品和放射自显影技术，并将提供 所有的科学家都有一个非常精确的数据分析系统， 迄今为止还没有以任何形式出现在这个重要的研究中心。

The proposal represents a coordinated effort to fill the needs of approximately 150 investigators who undertake research in molecular biology or protein chemistry and require sensitive, rapid quantitative analysis of techniques which rely for detection of a radioactive signal. The request is supported by a primary user group of sixty investigators who would use these instruments. Appropriate institutional support has been committed for technical consultants, placement of the instruments at two sites which would be convenient for all faculty who would use the instruments, provision of ancillary funds for purchase of peripheral data processing work-stations and software, and for networking the instruments to the peripheral computers for off-site data storage and manipulation. Plans for upkeep and maintenance of the instruments, scheduling of their judicious use, and access for junior unfunded investigators, have been provided. The instruments will be considered as part of the University's molecular resources core and will be administered by the advisory committee headed by Dr. George Abraham, Associate Dean for Research and Professor of Medicine, Dr. Barbara Iglewski, Professor and Chair of Microbiology and Immunology, Dr. Martin Gorovksy, Professor and Chair of Biology, Dr. Fred Sherman, Professor and Chair of Biochemistry, and Dr. Terry Platt, Professor of Biochemistry. The addition of these instruments to the Molecular Biology facility at the University and Medical School will be of great benefit to its investigators, will markedly diminish the need for and waste from radioactive chemicals and autoradiographic techniques, and will provide all scientists with a system for data analysis of excellent precision which has hitherto not been present in any form at this major research center.