Combating giardiasis by investigating new potent compound series as leads for improved treatment options
Combating giardiasis by investigating new potent compound series as leads for improved treatment options
批准号:
nhmrc : GNT1141069
负责人:
A/Pr Aaron Jex
金额:
$77.6万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
贾第鞭毛虫寄生虫感染了全球约10亿人,并造成了严重的发病率和劣势。没有获得许可的疫苗,目前的治疗方案不足,导致依从性差、治疗失败、快速再感染和耐药性。需要新的疗法来对抗这种寄生虫,并改善全世界数百万人的健康。我们将通过研究治疗贾第鞭毛虫感染的新候选药物来解决这个问题。
英文摘要
Giardia parasites infect ~1 billion people globally and are responsible for significant morbidity and disadvantage. There is no licensed vaccine and current treatment options are inadequate, resulting in poor compliance, treatment failures, rapid re-infection and drug resistance. New therapies are needed to combat this parasite and improve the health of millions world-wide. We will address this issue by investigating new drug candidates for the treatment of Giardia infections.
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Combating giardiasis by investigating new potent compound series as leads for improved treatment options
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批准号:nhmrc : 1141069
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项目类别:Project Grants
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资助金额:$52.47万
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财政年份:2018
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负责人:A/Pr Aaron Jex
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依托单位:
Systems biology of neglected parasites
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批准号:nhmrc : GNT1126395
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项目类别:Career Development Fellowships
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资助金额:$47.01万
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财政年份:2017
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负责人:A/Pr Aaron Jex
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依托单位:
Systems biology of neglected parasites
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批准号:nhmrc : 1126395
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项目类别:Career Development Fellowships
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资助金额:$32.12万
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财政年份:2017
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负责人:A/Pr Aaron Jex
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依托单位:
Genome-based tools to support urogenital schistosomiasis control
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批准号:nhmrc : GNT1102322
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项目类别:Project Grants
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资助金额:$42.96万
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财政年份:2016
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负责人:A/Pr Aaron Jex
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依托单位:
Genome-based tools to support urogenital schistosomiasis control
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批准号:nhmrc : 1102322
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项目类别:Project Grants
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资助金额:$29.53万
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财政年份:2016
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负责人:A/Pr Aaron Jex
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依托单位:
Discovering the function and structure of RIO kinases – toward new nematocides
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批准号:nhmrc : 1044022
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项目类别:Project Grants
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资助金额:$36.37万
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财政年份:2013
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负责人:A/Pr Aaron Jex
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依托单位:
An intergrated pipeline for understanding the molecular epidemiology of waterborne and zoonotic disease
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批准号:nhmrc : 628883
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项目类别:Career Development Fellowships
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资助金额:$14.58万
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财政年份:2010
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负责人:A/Pr Aaron Jex
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依托单位:
海外基金