EFFICACY OF PRISM ADAPTATION IN ACQUIRED ESOTROPIA

回顾性研究表明，只有50%的手术患者 后天性内斜视通过一次手术获得良好的眼位对准。 新 有证据表明，术前使用棱镜， 一次操作即可实现对准， 后天性内斜视的外科病人。 一项多中心、随机、 前瞻性临床试验，并仔细注意标准化和 建议进行公正的结果评价，以确定： 1.后天性内斜视的手术效果较好， 他们有术前棱镜适应比如果他们没有 术前棱镜适应。 2.如果那些对棱镜适应有反应的患者更准确地 通过对棱镜适配角或初始角进行操作来校正 偏差 3.如果存在输入变量的聚类（例如，年龄、偏差大小， 感觉状态、屈光不正或AC/A比率），有助于预测 患者更可能对棱镜适应测试作出反应。 为了回答这些问题，一项双随机研究 被设计。 三分之二的病人会被随机挑选 通过手术前的棱镜适应。 三分之一的患者会 根据常规测量的交叉量进行手术 检查技术。 在那些对棱镜有反应的病人中， 一半的人将根据所需的棱镜数量进行手术，

Retrospective studies indicate that only 50% of surgical patients with acquired esotropia achieve good eye alignment with one surgery. New evidence indicates that with the preoperative use of prisms, good eye alignment can be achieved with one operation in approximately 85% of surgical patients with acquired esotropia. A multicenter, randomized, prospective, clinical trial with careful attention to standardization and unbiased outcome evaluation is proposed to determine if: 1. The surgical result in patients with acquired esotropia is better if they have preoperative prism adaptation than if they do not have preoperative prism adaptation. 2. If those patients who respond to prism adaptation are more accurately corrected by operating for the prism adapted angle or the original angle of deviation. 3. If there are clusters of input variables, (e.g. age, size of deviation, sensory status, refractive error, or AC/A ratio) that help to predict which patients are more likely to respond to the prism adaptation test. In an effort to answer these questions a double randomization study has been designed. Two-thirds of the patients will be randomly selected to go through prism adaptation prior to surgery. One-third of the patients will have surgery based on the amount of crossing measured using routine examination techniques. Of those patients who respond to the prisms, one-half will have surgery based on the amount of prism required to