COMMUNITY CLINICAL ONCOLOGY PROGRAM

NSABP是一家由国家癌症研究所资助的国际 多学科合作临床试验小组，超过150人 成员机构。NSABP进行临床和其他 关于乳腺癌治疗的癌症控制研究 肠癌。在过去的25年里，它成功地 进行了一系列临床试验，其结果是 极大地改变了乳房和乳房患者的标准护理 肠癌。NSABP生物统计中心非常 具有丰富的设计、数据管理和分析经验 包括癌症控制试验在内的多机构研究。这个 数据的质量控制程序和教育计划 管理层都建立了良好的基础。目前，有六家 主动治疗方案解决佐剂中的问题 治疗原发性乳腺癌和肠癌。的范围 这些研究非常适合社区调查人员 构成了目前NSABP的相当大一部分 会员制。20名CCOP参与NSABP试验和 从1985年6月到1986年5月的12个月期间，他们进入了 242名患者，占同期总人数的11%。 这些CCOP成员实现了高标准的数据 可与其他成员机构相媲美的管理。 这项申请的目的是获得资金，使 NSABP将继续作为CCOP研究基地并扩大其 不仅提供治疗方案，还提供癌症控制 协议也是如此。

The NSABP is a National Cancer Institute funded international multidisciplinary cooperative clinical trial group with over 150 member institutions. The NSABP conducts clinical and other cancer control research concerning the treatment of breast and bowel cancer. Over the past 25 years it has successfully conducted a series of clinical trials, the results of which have dramatically altered the standard care of patients with breast and bowel cancer. The NSABP Biostatistical Center is very experienced in the design, data management and analysis of multi-institutional studies including cancer control trials. The quality control procedures and educational programs for data management are well established. At present, there are six active treatment protocols addressing questions in the adjuvant treatment of primary breast and bowel cancer. The scope of these studies is ideally suited for community investigators who comprise a significant proportion of the current NSABP membership. Twenty CCOP's participate in NSABP trials and in the 12-month period from June, 1985 to May, 1986, they entered 242 patients, 11% of the total group accrual for the same period. These CCOP members have achieved a high standard of data management which is comparable to other member institutions. The aim of this application is to obtain funds which will allow the NSABP to continue as a CCOP research base and to expand its role by providing not only treatment protocols but cancer control protocols, as well.