COMMUNITY CLINICAL ONCOLOGY PROGRAM-NSABP RESEARCH BASE

NSABP是一个由国家癌症研究所资助的国际组织， 多学科合作临床试验组， 成员机构。 NSABP开展临床和其他 关于乳腺癌治疗的癌症控制研究， 肠癌 在过去的25年里，它成功地 进行了一系列的临床试验，其结果 极大地改变了乳腺癌患者的标准护理， 肠癌 NSABP生物统计中心非常 具有丰富的设计、数据管理和分析经验， 包括癌症控制试验在内的多机构研究。 的 数据质量控制程序和教育计划 管理已经很好地建立。 目前，有6个 积极的治疗方案解决问题的辅助 治疗原发性乳腺癌和肠癌。 的范围 这些研究非常适合社区调查人员， 在目前的国家生物安保战略中占很大比例， 会员资格 20名CCOP参加了NSABP试验， 1985年6月至1986年5月的12个月期间，他们进入了 242例患者，占同期组总招募人数的11%。 缔约方会议协商委员会的这些成员取得了高标准的数据 与其他成员机构相比， 本申请的目的是获得资金， NSABP继续作为CCOP的研究基地，并扩大其 不仅提供治疗方案，还提供癌症控制， 协议，也是。

The NSABP is a National Cancer Institute funded international multidisciplinary cooperative clinical trial group with over 150 member institutions. The NSABP conducts clinical and other cancer control research concerning the treatment of breast and bowel cancer. Over the past 25 years it has successfully conducted a series of clinical trials, the results of which have dramatically altered the standard care of patients with breast and bowel cancer. The NSABP Biostatistical Center is very experienced in the design, data management and analysis of multi-institutional studies including cancer control trials. The quality control procedures and educational programs for data management are well established. At present, there are six active treatment protocols addressing questions in the adjuvant treatment of primary breast and bowel cancer. The scope of these studies is ideally suited for community investigators who comprise a significant proportion of the current NSABP membership. Twenty CCOP's participate in NSABP trials and in the 12-month period from June, 1985 to May, 1986, they entered 242 patients, 11% of the total group accrual for the same period. These CCOP members have achieved a high standard of data management which is comparable to other member institutions. The aim of this application is to obtain funds which will allow the NSABP to continue as a CCOP research base and to expand its role by providing not only treatment protocols but cancer control protocols, as well.