MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITS

本次提交的主要目的是重新申请指定 作为被选中参加新生儿网络的中心之一， 重症监护室。 迈阿密大学新生儿科 拥有足够的临床患者人群，出色的临床， 实验室和研究设施，以及有能力、有献身精神的人员。 它在个人调查工作中具有丰富的研究经验 以及大型多中心临床试验。 的 迈阿密大学积极参与了最初的5年周期 NICU网络。 虽然在低收入国家中一直排名第三， 出生体重新生儿入院，他们一直排名第一， 随机进入第一个主要网络试验的婴儿总数 预防性静脉注射免疫球蛋白。 他们有 在其他大型多中心成功的丰富经验 临床试验，如产前糖皮质激素给药（NHLBI）， 高频通气（NHLBI）。以及婴儿的健康和发展 程序（罗伯特·伍德约翰逊）。 他们致力于实现 该网络的目的是评估新药物的安全性和有效性， 使用大型多地点随机临床试验的治疗方式， 而不是有限的个人经验或偏好。 大学 有大量的母婴新生儿 每年大约有14,000例活产分娩。 此外，它还服务于 作为一个地区的三级区域转诊中心， 40，000名新生儿，并从中央和地方政府接受县外转诊， 南美洲和加勒比海。 新生儿特别护理中心 通常进行超过120- 130%的人口普查。 高风险团队现在 包括200多名全职人员，他们的工作专门致力于 新生儿及其家人。 医学系拥有广泛的 肺和发育医学领域的专业知识， 滥用和传染病及中枢神经系统疾病。 一项长期 多学科发展评估和干预计划是 由提议的私人侦探指导迈阿密大学致力于 相关的临床研究，其现有的人口，设施和 人员，以及过去一年来成功合作的良好记录 十年来，有强烈的愿望继续在新生儿ICU网络， 有助于有效解决复杂的诊断和治疗问题， 新生儿的问题。

The primary objective of this submission is to re-apply for designation as one of the centers selected to participate in the Network of Neonatal Intensive Care Units. The University of Miami's Division of Neonatology possesses an adequate clinical patient population, outstanding clinical, laboratory and research facilities, and competent, dedicated personnel. It has an extensive research experience in individual investigative work as well as in large collaborative multicenter clinical trials. The University of Miami has actively participated in the initial 5 year cycle of the NICU Network. Although consistently ranking third in number of low birth weight neonatal admissions, they have consistently ranked first in total numbers of infants randomized into the first major network trial on prophylactic intravenous immunoglobulin administration. They have extensive previous experience in other large multi-center successful clinical trials, such as prenatal glucocorticoid administration (NHLBI), high frequency ventilation (NHLBI. and the infant health and development program (Robert Wood Johnson). They are dedicated to the underlying goal of the Network which is to evaluate both the safety and efficacy of new therapeutic modalities using large multi-site randomized clinical trials, as opposed to limited personal experience or preference. The University of Miami has access to a large maternal-fetal-neonatal population approximating 14,000 live-born deliveries per year. In addition, it serves as the tertiary regional referral center for an area encompassing over 40,000 births and it receives out of county referrals from Central and South America and the Caribbean. The Neonatal Special Care Center routinely runs a census exceeding 120-130%. The high-risk team now includes over 200 full-time personnel whose work is exclusively devoted to neonates and their families. The neonatology faculty possess a wide range of expertise in areas of pulmonary and developmental medicine, substance abuse and infectious and central nervous system disorders. A longterm multi-disciplinary developmental evaluation and intervention program is directed by the proposed P.I. The University of Miami, with its commitment to relevant clinical research, its existing population, facilities and personnel, and its proven record of successful collaboration over the last decade, has a strong desire to continue in the Neonatal ICU Network and to contribute to effectively addressing the complex diagnostic and therapeutic problems of the newborn.