OMEGA 3 FATTY ACIDS--EFFECT ON INSULIN AND GLUCOSE METABOLISM

本研究将估计肝血流量和肝内血流。 使用吲哚菁绿色和茶碱的正常人的清除率， 将这些由矩分析确定的估计值与 另一种方法只需要一个或两个血液样本。 后 在法线中验证，此方法将用于确定 重症患者的肝功能。 该研究还将 试图估计药物的药代动力学消除的 在危重病人的肝脏。

This study will estimate hepatic blood flow and intrinsic hepatic clearance in normals using indocyanine green and theophylline and compare these estimates determined by moment analysis to an alternate method requiring only one or two blood samples. After validation in normals, this method will be used to determine hepatic function in critically ill patients. The study will also attempt to estimate the pharmacokinetics of drugs eliminated by the liver in the critically ill patient.