OMEGA 3 FATTY ACIDS--EFFECT ON INSULIN AND GLUCOSE METABOLISM

正常受试者将有葡萄糖，胰岛素，欧米茄3和欧米茄6脂肪酸 在基线时进行正葡萄糖钳夹研究， 测定外周胰岛素敏感性。 一半的实验对象 饮食中含有30%的欧米茄6，不含欧米茄3脂肪酸， 一半人将在4周内摄入20%的欧米茄3和<1%的欧米茄6。 3周后 淘汰后，各组将逆转饮食。 将重复基线研究 在每个时期结束时。

Normal subjects will have glucose, insulin, Omega 3 and Omega 6 fatty acid determinations at baseline followed by a euglycemic clamp study to determine peripheral insulin sensitivity. Half the subjects will be placed on diets of 30% Omega 6 and no Omega 3 fatty acid while the other half will consume 20% Omega 3 and <1% Omega 6 for 4 weeks. After a 3 week washout, the groups will reverse diets. Baseline studies will be repeated at the end of each period.