RESEARCH AND TRAINING FOR BIOMEDICAL CAREER DEVELOPMENT

在约克学院MBRS计划的目标-“研究和 生物医学职业发展培训”-是为了提高和 加强研究环境，扩大研究范围， 自然科学系的生物医学研究， 健康教育，主要目的是为我们的少数民族提供 学生获得知识的机会增加 专业知识和动机，将（a）引导他们走向职业生涯 （B）能够成功地竞争 研究生院和专业学校的职位。 支持是 要求提供免疫学、微生物遗传学、 有机和物理化学以及3个细胞生物学新项目， 有机化学和流行病学。 还要求支持 21名学生将参与规划的所有阶段， 研究的执行情况，以及报告和 公布结果。 在项目#1中，肺泡特性 损伤肺上皮细胞”，肺的机制， 将研究对化学诱导的损伤的反应。 在 项目#2，“雄激素敏感性作为免疫能力的一个因素”， 高雄激素应答小鼠的低免疫应答将是 研究了 在项目#3，“简单的电子光谱学 卟啉和细菌视紫红质”， 将研究模式生物发色团。 在项目#4中， “庆大霉素诱导的细菌变异细胞形成”， 转座事件在产生诱导抗性细胞中的作用 将被审查。 项目#5，“抗病毒的新方法 核苷类似物”，将开发一种新的途径，核苷 合成. 在项目#6中，“生活方式因素与 静脉注射药物滥用者（IVDAs）与艾滋病”，历史和 药物滥用及其治疗状况以及性取向和 这一群体的社会经济状况将得到研究。 在项目 #7，“用于蛋白质NMR的独特标记的氨基酸”，2 H，13 C和 15 N标记的氨基酸将被合成并掺入到 通过溶液和固态NMR进一步研究蛋白质。

The objectives of the MBRS program at York College - "Research and Training for Biomedical Career Development" - are to improve and strengthen the research environment and to broaden the scope of biomedical research in the departments of Natural Sciences and Health Education, for the primary purpose of providing our minority students with increased opportunities to acquire the knowledge expertise and motivation that will (a) direct them towards careers in biomedical research and (b) enable to successfully compete for positions in graduate and professional schools. Support is requested for 4 ongoing projects in immunology, microbial genetics, organic and physical chemistry and 3 new projects in cell biology, organic chemistry and epidemiology. Support is also requested for 21 students who will participate in all phases of the planning and implementation of the research, as well as in the reporting and publication of the results. In project #1, Properties of Alveolar Epithelial Cells from Injured Lung", the mechanism of the pulmonary response to chemically-induced injury will be investigated. In project #2, "Androgen Sensitivity as a Factor in Immunocompetence", low immune response of high androgen responder mice will be studied. In project #3, "Electronic Spectroscopy of Simple Porphyrins and Bacteriorhodopsin", excited electronic states of model biological chromophores will be studied. In project #4, "Gentamycin-Induced Variant Cell Formation in Bacteria", the role of transposition events in producing the induced resistant cells will be examined. Project #5, "A New Approach to Antiviral Nucleoside Analogues", will develop a novel route to nucleoside synthesis. In project #6, "Lifestyle factors associated with Intra-Venous Drug Abusers (IVDAs) with AIDS", the history and status of drug abuse and its treatment, and sexual orientation an socioeconomic status in this group, will be studied. In project #7, "Uniquely labelled Amino Acids for Protein NMR", 2H, 13C and 15N labelled amino acids will be synthesized and incorporated into proteins for further study by solution and solid state NMR.