INSIGHT - medIcal oxygen supply chaiN deSIGn and planning for COVID-19 HospiTals

随着SARS-CoV-2大流行的演变变得越来越不确定，氧疗成为目前患者的主要治疗方法，确保医用氧气供应链的弹性和强健运行变得越来越迫切。Insight将针对当前和未来的SARS-CoV-2疫情以及其他需要紧急计划的流行病和病例，对英国医用氧气供应链的综合设计和运营进行全系统分析。洞察力的一个关键独特性是对供应链进行空间上明确的、具有不确定性意识的建模，这将为区域特定战略提供路线图，并根据对未来新冠肺炎浪潮的不同实现来实施。我们基于优化的应急计划增强决策框架将是开源的、公开可用的，由于洞察的设计，可以很容易地推广到欧洲和中低收入国家(LMIC)的战略。为此，我们建议结合供应链优化、多尺度建模和随机优化的方法。通过与Linde.plc的长期合作，我们一直在开发与空分行业相关的型号。最后，我们获得了两家NHS散装医用氧气供应商之一中银的积极参与，以最大限度地发挥洞察力成果的影响和适用性。

With the evolution of the ongoing SARS-CoV-2 pandemic becoming increasingly uncertain andoxygen-therapy being the current dominant treatment of patients, securing resilient and robustoperation of medical oxygen supply chains becomes increasingly urgent. INSIGHT will develop a whole-systems analysis on the integrated design and operation of medical oxygen supply chains inthe UK for current, future waves of SARS-CoV-2 as well as for other pandemics and cases thatrequire emergency planning. A key uniqueness of INSIGHT is the spatially-explicit and uncertainty-awaremodelling of supply chains which will provide a roadmap to region-specific strategies forcoping with different realisations of future COVID-19 waves. Our optimisation-based framework for enhanced decision making for emergency planning will be open-source, publicly available anddue to the design of INSIGHT could be easily generalised to inform European and low and middle incomecountries (LMICs) strategies. To this end, we propose to combine methodologies fromsupply chain optimisation, multi-scale modelling and stochastic optimisation. Throughour long-standing collaboration with Linde.plc we have been developing models related to the airseparation industry. Finally, we have secured the active participation of BOC, one of the two NHSbulk medical oxygen providers, so as to maximise the impact and applicability of INSIGHT'soutcomes.