课题基金 / 基金详情

EFFECTS OF MATERNAL PKU ON PREGNANCY OUTCOME

EFFECTS OF MATERNAL PKU ON PREGNANCY OUTCOME
母亲 PKU 对妊娠结局的影响
批准号：
3650832
负责人：
REUBEN MATALON
金额：
$15.63万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1984
资助国家：
美国
项目状态：
已结题
起止时间：
1984-05-16 至 1991-05-15
来源：
https://reporter.nih.gov/project-details/3650832
关键词：
academic achievement child (0-11) child physical development child psychology diet therapy embryo /fetus homozygote human population genetics human subject mother /embryo /fetus nutrition nutrition disorder chemotherapy nutrition related tag perinatal phenylalanine phenylketonurias

项目摘要

项目成果

REUBEN MATALON的其他基金

相关文献

中文摘要
翻译
维持正常妊娠所需的母体苯丙氨酸水平。 在怀孕的哪个阶段，低苯丙氨酸饮食对 预防母体PKU对发育中胎儿的影响。如果 低苯丙氨酸饮食的有益效果可以在以下情况下得到改善 在受孕之前开始，而不是在受孕后。无论是 节食可减少智力低下、自然流产、 低出生体重、先天畸形、神经和行为 高苯丙氨酸血症母亲的婴儿中发现的损害。 妊娠期间的酪氨酸和微量金属水平，并确定 如果发现水平低则补充对妊娠的影响 结果。
英文摘要
The level of maternal phenylalanine which will maintain a normal pregnancy. At what stage of pregnancy a low phenylalanine diet is most effective in preventing the effects of maternal PKU on the developing fetus. If the beneficial effects of a low phenylalanine diet can be improved when initiated prior to conception compared to post-conception. Whether the diet reduces the frequency of mental retardation, spontaneous abortions, low birth weight,congenital malformations, neurological and behavioral impairment found in infants of mothers with hyperphenylalaninemia.The levels of tyrosine and trace metals during pregnancy and ascertain the effects of supplementation if levels are found to be low on pregnancy outcome.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
RESPONSE OF PHENYLKETONURIA TO TETRAHYDROBIOPTERIN (BH4)
RESPONSE OF PHENYLKETONURIA TO TETRAHYDROBIOPTERIN (BH4)
RESPONSE OF PHENYLKETONURIA TO TETRAHYDROBIOPTERIN (BH4)
Phenylalanine Hydroxylase Deficiency: Response to BH4