ULTRASOUND ESTIMATIONS FOR PULMONARY ARTERY PRESSURE

该项目的目的是开发一种非侵入性技术，用于 基于记录获得的肺动脉压的估计 心肺中心研制的多普勒仪样机 科罗拉多大学健康科学中心的研究实验室。 在项目的第一阶段，调查人员将重点放在分析上 速度和时间的一些变化之间的关系 认为发生在肺动脉压升高和肺动脉高压的情况下 心导管插入术中无创测量动脉压。这个 这些分析的重点将是提供参数的组合 可预测不同年龄组个体的肺动脉压。 条件多种多样。该项目将专注于之前的录音 使用原型仪器获得的数据，尽管新数据将继续 被收集起来。多谱勒扫描的回顾和前瞻性研究 与导管相比，数据将被执行以尝试 肺动脉压的多谱勒信号特征。如果可靠 可以找到关系的信号处理算法将 在第二阶段的工作中被合并到专用仪器中。这个 这种方法看起来很有希望，尽管变量的数量 对于六个月的研究来说，调查的规模很大。

The purpose of this project is to develop a noninvasive technique for the estimation of pulmonary artery pressure based recordings obtained with a prototype doppler instrument developed by the Cardiovascular Pulmonary Research Laboratory at the University of Colorado Health Science Center. During Phase 1 of the project the investigators will focus on the analysis of the relationship between a number of changes in velocity and timing thought to occur with elevated pulmonary artery pressure and pulmonary artery pressure measured invasively during cardiac catheterization. The focus of these analyses will be to provide a combination of parameters which predict pulmonary artery pressure in a variety of individuals under a variety of conditions. The project will focus on recordings previously obtained with the prototype instrument, although new data will continue to be collected. Retrospective and prospective studies of Doppler scans as compared to catheter data are to be performed in an attempt to relate Doppler signal characteristics to pulmonary artery pressure. If reliable relationships can be found the signal processing algorithms will be incorporated into a dedicated instrument during a Phase II effort. The approach appears promising although the number of variables to be investigated is large for a six month study.