Control of neuropeptide FF receptors on appetite and energy homeostasis

尽管肥胖的流行令人担忧，但目前还没有有效的长期治疗方法。神经肽FF及其受体NPFF2R在调节食物摄入和体脂储存方面发挥着新的作用。本研究的结果将显示NPFF2R是否在调节食欲、代谢率、体重和脂肪储存方面发挥重要作用，从而有助于确定以NPFF2R为靶点的治疗方法是否能为肥胖症的长期治疗带来显著益处。

Despite the alarming obesity epidemic, there currently exists no effective long-term treatment for obesity. Neuropeptide FF and its receptor NPFF2R have an emerging role in regulating food intake and body fat stores. Results from this study will show whether NPFF2R plays an important role in regulating appetite, metabolic rate, body weight and fat stores, thus help to identify whether NPFF2R-targeted therapeutics would confer significant benefit for the long-term treatment of obesity.