COOPERATIVE BREAST CANCER TISSUE REGISTRY

美国国家癌症研究所（NCI）建议建立一个多- 机构合作乳腺癌组织登记处（CBCTR）作为一种手段， 采购和分发石蜡包埋的乳腺癌档案 来自具有已知临床结果的患者的组织，以支持 研究人员验证潜在的预后和治疗标志物。 每年有250多例新的乳腺癌被诊断出来， 种族多样的美国黑人。西班牙裔和非 由迈阿密大学/杰克逊纪念馆服务的西班牙裔白人 医院;目前约有4，000名乳腺癌患者 在我们的临床数据库中注册了该提案描述了 人员、患者临床数据和组织资源 CBCTR待注册组织的类别、选择方法， 储存和检索相关组织，协调临床 数据和组织，组织的适当制备以供分发 研究人员和质量机制，以实现目标 书记官处。使用多余的组织进行 研究也得到了解决。迈阿密大学/杰克逊纪念馆 医院是一个很好的网站为一个分支，这个国家癌症研究所主办的 合作登记处并承诺全力合作以实现其目标。

The National Cancer Institute (NCI) has proposed creating a multi- institutional Cooperative Breast Cancer Tissue Registry (CBCTR) as a means of procuring and distributing archived paraffin embedded breast cancer tissues from patients with a known clinical outcome to support investigators validating potential prognostic and therapeutic markers. More than 250 new breast cancers are diagnosed each year among the ethnically diverse population of American blacks. Hispanics and non- Hispanic whites served by the University of Miami/Jackson Memorial Hospital; approximately 4,000 breast cancer patients are currently registered in our clinical data base. This proposal describes the personnel, patient clinical data and tissue resources available to the CBCTR the categories of tissues to be registered, the means of selecting, storing and retrieving pertinent tissues, the coordination of clinical data and tissues, the appropriate preparation of tissues for distribution to investigators and the quality mechanisms necessary to achieve the goals of the Registry. The medicolegal aspects of the use of excess tissue for research are also addressed. The University of Miami/Jackson Memorial Hospital is an excellent site for a branch of this NCI-sponsored Cooperative Registry and pledges full cooperation to achieve its goals.