Coordinating leukocyte migration and interaction during immune responses: the multiple and central roles of the orphan G protein coupled receptor EBI2

免疫系统抵抗感染的能力依赖于免疫细胞在体内导航的能力。本研究旨在了解免疫细胞受体Epstein-Barr病毒诱导基因2(EBI2)在免疫应答中引导不同类型白细胞运动和相互作用的作用。这些见解将增加我们对免疫细胞迁移的理解，从而为改善或控制免疫反应提供新的治疗方法。

The ability of the immune system to fight infections relies on the capacity of immune cells to navigate within the body. This study aims at understanding the role of the immune cell receptor Epstein-Barr virus-induced gene 2 (EBI2) in guiding the movement and the interaction of the different types of white blood cells during immune responses. These insights will add to our understanding of immune cell migration thereby offering new therapeutic approaches to improve or control immune responses.