COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY

此应用程序的目的是记录奥尔巴尼的能力 医学院眼科将作为 在拟建的多中心中建立高效、多产的临床中心 临床试验，题为“协作初始青光眼治疗研究” (CIGTS)。这项研究的目的是评估最初的治疗 治疗开角型青光眼更有效的方法是采用阶梯式、内侧式青光眼 治疗方案或通过外科手术方法。奥尔巴尼医学院 临床中心将通过确定和 招募符合条件的患者，实施如下治疗方案 由CIGTS协调中心指定，并在 研究操作手册，跟踪和留住研究患者， 记录研究数据并将其传输到协调中心，以及 对将介绍CIGTS结果的报告作出贡献。作为一名 协作性初始青光眼治疗研究临床中心， 奥尔巴尼医学院青光眼服务部 狮子眼科研究所眼科提供最先进的临床 青光眼诊断和治疗研究机构。三位一体 研究人员在青光眼研究方面拥有丰富的经验，并 专业于青光眼的大型咨询诊所(大于15， 青光眼患者就诊人次/年)。此外，26个社区委员会 注册眼科医生已登记积极参与 这是研究中的中心。作为一个整体，他们提供了一个巨大的临床基础 在纽约东北部(每年超过15万人次) 从而最大限度地促进患者招募和护理。在3个月的试用期中 使用《手册》中概述的标准为这项研究招募人员 手术，该中心确定了18名符合条件的患者，代表 有足够的潜力招募病人(附录1)。这个中心 预计每月招募3名患者参与这项研究。 研究人群将包括性别和各种不同性别的患者 符合这一地理区域的种族和种族背景 这个国家。提供了我们的计划的详细信息，以确定、招募、 关注并留住这些患者，我们的意图一直很高 关于治疗的视觉结果的高质量数据，以及人员和 我们中心内的设施可用于执行本规定 CIGTS的操作手册。

The intent of this application is to document the ability of the Albany Medical College, Department of Ophthalmology to participate as an effective and productive clinical center in the proposed multicenter clinical trial, entitled "Collaborative Initial Glaucoma Treatment Study" (CIGTS). This study's purpose is to evaluate whether initial treatment of open angle glaucoma is more effective by means of a stepped, medial regimen or by means of a surgical approach. The Albany Medical College's Clinical Center will participate in the CIGTS by identifying and recruiting eligible patients, administering the treatment regimen as assigned by the CIGTS's Coordinating Center and defined within the study's Manual of Operations, following and retaining study patients, recording and transferring study data to the Coordinating Center, and contributing to reports that will present the CIGTS results. As a clinical center in the Collaborative Initial Glaucoma Treatment Study, the Glaucoma Service at the Albany Medical College, Department of Ophthalmology, Lions Eye Institute, offers a state of the art clinical research facility for the diagnosis and treatment of glaucoma. The three investigators have extensive experience in glaucoma research and have large consultative practices specializing in glaucoma ( greater than 15, 000 glaucoma patient visits /year) . In addition, 26 community board certified ophthalmologists have enrolled to actively participate with this center in the study. As a group, they offer a large clinical base in Northeastern New York ( greater than 150,000 patient visits/year) which maximizes patient recruitment and care. In a 3 month trial recruitment for this study using the criteria outlined in the Manual of Operations, this center identified 18 qualifying patients, representing adequate potential for patient recruitment (Appendix 1). This center expects to recruit 3 patients per month for participation in this study. The study population will include both sexes and patients of a variety of ethnic and racial backgrounds consistent with this geographical region of the country. Details are provided of our plans to identify, recruit, follow, and retain these patients, our intent to obtain consistently high quality data on the visual outcomes of treatment, and the personnel and facilities available within our center to carry out the provisions of the CIGTS's Manual of Operations.