ADJUVANT BREAST AND COLORECTAL CANCER THERAPY

此应用程序请求支持人员，运营费用和 与在联合国药物管制规划署开展合作临床试验有关的差旅费 肯塔基州大学的赞助下，国家外科佐剂 乳腺和肠道项目（NSABP）。这种支持将巩固和加强 该机构已经为NSABP计划做出了重大贡献 (206患者在过去四年中增加）。 在露西尔帕克 马基癌症中心，该大学已经制定了一个健全的框架 以促进这些研究。 该框架基于一个 临床研究办公室负责协调和监测几乎所有 临床肿瘤学协议在大学，现在也作为 国家合作小组研究的行政渠道 已经在整个州的社区肿瘤学实践中被激活， 肯塔基州。 本提案所要求的资金将用于支持和 通过大学加强参与NSABP议定书 肯塔基州计划通过（1）确保持续增长的应计和优秀的 NSABP乳腺癌和结直肠癌患者的数据管理 大学，（2）为不断增长的应计费用提供部分薪金支持， 五个附属机构的数据管理需求， 已建立的临床研究计划，以及（3）提供现场数据 缺乏当地资源的六个附属地点的管理 用于监测研究患者。 需要大量差旅支助 允许主要参与人员参加适当的正式会议， 国家生物安保局指定的会议。

This application requests support for personnel, operating expenses and travel related to the conduct of cooperative clinical trials at the University of Kentucky under the auspices of the National Surgical Adjuvant Breast and Bowel Project (NSABP). This support will solidify and enhance an already substantial contribution by this institution to the NSABP program (206 patients accrued over the past four years). Within the Lucille Parker Markey Cancer Center, the University has developed a sound framework through which to facilitate such studies. This framework is based in a Clinical Research Office which coordinates and monitors virtually all clinical oncology protocols at the University and now serves also as the administrative conduit through which national cooperative group studies have been activated in community oncology practices throughout the state of Kentucky. The funds requested in this proposal are to support and consolidate participation in NSABP protocols through the University of Kentucky program by (1) ensuring continued growth in accrual and excellent data management for NSABP breast and colorectal cancer patients at the University, (2) providing partial salary support for growing accrual and data management demands at five affiliate institutions with already established clinical research programs, and (3) providing on-site data management at six affiliate locations at which local resources are lacking for monitoring patients on study. Significant travel support is requested to permit key participating personnel to attend appropriate officially designated meetings of the NSABP.