BARBADOS INCIDENCE STUDY OF EYE DISEASE (BISED)

巴巴多斯眼病发病率研究（BISED）旨在 提供开角型青光眼（OAG）和其他主要青光眼的流行病学数据， 黑人视力丧失的原因 它旨在确定 OAG，年龄相关性白内障， 年龄相关性黄斑变性、糖尿病视网膜病变和视力 在约4500人的人群中， 年龄40-86岁，1988-1992年接受检查， 巴巴多斯眼科研究（BES）。 BES旨在测量患病率 和风险因素的每一个主要的眼睛疾病在黑色 并为未来的发病率建立基线 测量. 从未有过发生率或进展数据 收集的关于黑人眼疾的数据， 高参与率（85%）的患病率研究， 人口，以便进行精确估计和风险因素评估， 以及标准化和可重复的临床和摄影方案 来衡量每一种疾病。 为了实现这些目标，BES的参与者将接受重新审查，以获得 视觉数据（例如，眼内压，屈光，视力， 视野、透镜分级）、血压和人体测量 测量、病史和其他访谈数据、立体眼底 椎间盘、黄斑和糖化血红蛋白的照片， 相同的BES协议 BES和BISED数据的比较不仅 提供急需的发病率和进展数据，但也将 允许风险因素评估和相对确定， 人群归因风险。 基线风险因素数据包括 心血管变量，糖尿病和体型，眼部变量，使用 营养补充剂、药物暴露、吸烟和饮酒 使用，色素沉着，家族聚集，遗传标记，人口统计学 和卫生保健利用措施。 这些信息将提供 公共卫生规划的数据，了解病因，确定 制定适当的战略， 视力丧失 BISED的可行性得到了一项试点研究的支持 有94%的参与率和91%的积极反应， 回复一次检查。

The Barbados Incidence Study of Eye Diseases (BISED) is designed to provide epidemiologic data on open-angle glaucoma (OAG) and other major causes of visual loss in black populations. It aims to determine incidence, progression and risk factors for OAG, age-related cataract, age-related macular degeneration, diabetic retinopathy and visual impairment among the population-based cohort of about 4500 persons, ages 40-86 years, who were examined from 1988-1992 as part of the Barbados Eye Study (BES). The BES was designed to measure prevalence and risk factors for each of the major eye diseases in a black population and to establish a baseline for future incidence measurements. No incidence or progression data have ever been collected on eye diseases in blacks that are based on a nationwide prevalence study with a high (85%) participation, a sufficiently large population to allow both precise estimates and risk factor assessment, and standardized and reproducible clinical and photographic protocols to measure each disease. To achieve these aims, BES participants would be re-examined to obtain ocular data (e.g., intraocular pressure, refraction, visual acuity, visual fields, lens gradings), blood pressure and anthropometric measurements, medical history and other interview data, stereo fundus photographs of the disc and macula and glycated hemoglobin, following the same BES protocol. Comparison of BES and BISED data would not only provide much needed data on incidence and progression, but would also allow risk factor evaluation and determination of relative and population attributable risks. Baseline risk factor data include cardiovascular variables, diabetes and body size, ocular variables, use of nutritional supplements, medication exposures, smoking and alcohol use, pigmentation, familial aggregation, genetic markers, demographic and health care utilization measures. The information will provide data for public health planning, understanding etiology, identifying groups at high risk and developing appropriate strategies to control visual loss. The feasibility of BISED was supported by a pilot study that had a 94% participation rate and a 91% positive response to a response to a return examination.