Holographic Integrated Photonics Platform for the Optical Analysis of Biological Samples

我们提出了一个集成的光子平台的基础上全息元表面（HIPPO）的高通量微流体环境中的生物样品的imaging。该集成平台将高空间分辨率和大视场采集与现代筛选技术的吞吐量要求相结合。目前的解决方案依赖于复杂的照明系统和庞大的成像装置，以增加空间光谱范围和减少背景荧光。该项目的目标是将复杂性转移到便携式光流体芯片上，为每个生物学实验室的高通量检测铺平道路，将高通量和高分辨率显微镜变成生物学家的工具，而不是生物学家。

We propose to develop an integrated photonic platform based on holographic metasurfaces (HIPPO) for the high-throughputimaging of biological specimens in microfluidic environments. The integrated platform combines high spatial resolution and largefield of view acquisition with the throughput requirements of modern screening techniques. Current solutions rely upon complexillumination systems and bulky imaging setups to increase the spatial spectrum range and reduce the background fluorescence.The goal of this project is to move the complexity to a portable optofluidic chip and pave the way for high-throughput assays in everybiology lab, turning high-throughput and high-resolution microscopy into an instrument for biologists, rather than for biophysicists.