GENERAL CLINICAL RESEARCH CENTER

威斯康星大学医学院的这项请求是为了 额外的五年，从12月1日开始，，到11月 30,1994年，支持目前在ITS中的综合临床研究中心 运营第4年。 请求的支持是一个独立的中心，面向青少年-成年人 地理住院-门诊中心(天数/就诊人次/年)：住院患者： AS-1413，BS-320(6张床位，入住率79%)；门诊：AS-2368，BS-529； 和儿科年龄分散床位的住院-门诊支持 (天数/人次/年)：住院患者：AS-144，BS-709；门诊：AS-56， BS-237。与艾滋病有关的研究申请数为(天数/访问次数/年)： 住院患者：AS-176；门诊：AS-461。在本申请中31 同行审查和支持教职员工首席研究员和44名高度 代表21大学的合格教职员工联合调查员 威斯康星州的科室贡献了46个多学科临床 研究方案。威斯康星大学有着悠久的传统 基础和临床跨学科研究及其医学院和 威斯康星大学医院和诊所提供极好的 富有想象力的临床研究环境。这项研究 提交的方案代表了同行评审的基础和临床科学 研究人员在当前和重要的医学主题中的倡议 重要性。除艾滋病外，重点研究的领域包括 早产儿和囊肿症儿童的肺部问题 纤维化；矿物质对年轻人的营养影响；以及 肌萎缩侧索硬化症患者；生物免疫学 反应调节剂；哮喘和骨髓移植中的免疫因素； 成人睡眠障碍；视杆敏感的眼科研究， 和青光眼；糖尿病代谢紊乱，脂肪代谢，乳酸 酸中毒、盐分、情绪和抑郁以及母乳；生理效应 体温过高、免疫学和其他药物；药代动力学 癌症患者细胞毒药物的参数；生理学 护理程序的影响；以及以下方面表现出的心理社会角色 压力下的父母。教育机会的主要重点 医科学生、管家、博士后研究员和专职健康 强调临床研究方面的实习生。的长期目标是 这个GCRC将对新知识做出重大贡献 通过有组织的跨学科研究实现生物医学科学 学院基础科学和临床研究人员的活动 威斯康星大学。

This request by the University of Wisconsin Medical School is for an additional five-year period beginning December 1, 1989 through November 30, 1994 in support of the General Clinical Research Center now in its 4th year of operation. Requested support is as a Discrete Center and is for an adolescent-adult geographic inpatient-outpatient center of (days/visits/year): Inpatient: As-1413, Bs-320 (6 beds at 79% occupancy); outpatient: As-2368, Bs-529; and pediatric age scatter bed inpatient-outpatient support of (days/visits/year): inpatient: As-144, Bs-709; Outpatient: As-56, Bs-237. Requested for AIDS-related research are (days/visits/year): Inpatient: As-176; Outpatient: As-461. In this application 31 peer-reviewed and supported faculty principal investigators and 44 highly qualified faculty co-investigators representing 21 University of Wisconsin Departments have contributed 46 multidisciplinary clinical research protocols. The University of Wisconsin has a long tradition of basic and clinical interdisciplinary research, and its medical school and University of Wisconsin Hospital and Clinics offer an excellent environment for imaginative clinical investigations. The research protocols submitted represent peer-reviewed basic and clinical science investigator initiatives in topics of current and significant medical importance. Areas of focused study in addition to AIDS, include pulmonary problems in premature infants, and children with cystic fibrosis; nutritional effects of minerals in young individuals, and patients with amyotrophic lateral sclerosis; immunology of biological response modifiers; immunologic factors in asthma and marrow transplant; disorders of sleep in adults; ophthalmologic studies of rod sensitivity, and glaucoma; metabolic disorders of diabetes, fat metabolism, lactic acidosis, salt, mood and depression, and human milk; physiologic effects of hyperthermia and immunologic and other agents; pharmacokinetic parameters of cytotoxic agents in patients with cancer; physiologic effects of nursing procedures; and psychosocial roles exhibited by parents under stress. Major emphases on educational opportunities for medical students, houseofficers, post-doctoral fellows, and allied health trainees in clinical research are stressed. The long term objective of this GCRC is to make significant contributions to new knowledge in biomedical science through organized interdisciplinary research activities of faculty basic science and clinical investigators at the University of Wisconsin.