COOPERATIVE BREAST CANCER TISSUE REGISTRY

美国国家癌症研究所(NCI)建议建立一个多学科的 机构合作乳腺癌组织登记(CBCTR)作为一种手段 获取和分发存档的石蜡包埋乳腺癌 来自已知临床结果的患者的组织支持 研究人员验证潜在的预后和治疗标记物。 每年有超过250例新的乳腺癌被诊断出来。 种族多元化的美国黑人人口。拉美裔和非西班牙裔 迈阿密大学/杰克逊纪念馆服务的西班牙裔白人 医院；目前约有4000名乳腺癌患者 注册在我们的临床数据库中。本提案描述了 人员、患者临床数据和组织资源可供 拟登记组织的种类，选择的方法， 存储和检索相关组织，协调临床 数据和组织，适当准备组织进行分配 对调查人员和实现目标所需的质量机制 注册处的地址。使用多余组织治疗的法医学问题 此外，还介绍了相关研究。迈阿密大学/杰克逊纪念馆 医院是NCI赞助的一个分支机构的绝佳地点 合作登记处，并保证全力合作以实现其目标。

The National Cancer Institute (NCI) has proposed creating a multi- institutional Cooperative Breast Cancer Tissue Registry (CBCTR) as a means of procuring and distributing archived paraffin embedded breast cancer tissues from patients with a known clinical outcome to support investigators validating potential prognostic and therapeutic markers. More than 250 new breast cancers are diagnosed each year among the ethnically diverse population of American blacks. Hispanics and non- Hispanic whites served by the University of Miami/Jackson Memorial Hospital; approximately 4,000 breast cancer patients are currently registered in our clinical data base. This proposal describes the personnel, patient clinical data and tissue resources available to the CBCTR the categories of tissues to be registered, the means of selecting, storing and retrieving pertinent tissues, the coordination of clinical data and tissues, the appropriate preparation of tissues for distribution to investigators and the quality mechanisms necessary to achieve the goals of the Registry. The medicolegal aspects of the use of excess tissue for research are also addressed. The University of Miami/Jackson Memorial Hospital is an excellent site for a branch of this NCI-sponsored Cooperative Registry and pledges full cooperation to achieve its goals.