BARBADOS INCIDENCE STUDY OF EYE DISEASE (BISED)

巴巴多斯眼病发病率研究旨在 提供开角型青光眼(OAG)和其他主要疾病的流行病学数据 黑人人群中视力丧失的原因。它的目的是确定 OAG的发病率、进展和危险因素、年龄相关性白内障、 老年性黄斑变性、糖尿病视网膜病变和视力 在以人口为基础的队列中约有4500人受到损害， 年龄40-86岁，1988-1992年作为检查的一部分 巴巴多斯眼科研究(BES)。BES的设计是为了测量流行率 以及每一种主要眼病的风险因素 并为未来的发病率建立一个基线 测量。从来没有发生或进展的数据 关于黑人眼病的收集是基于全国范围内的 参与率高(85%)的流行率研究，足够大 人口允许进行精确估计和风险因素评估， 以及标准化和可重复性的临床和照相方案 来测量每一种疾病。 为了实现这些目标，BES参与者将被重新审查，以获得 眼睛数据(例如，眼压，屈光度，视力， 视野、镜片分级)、血压和人体测量 测量，病史和其他面谈数据，立体眼底 视盘、黄斑和糖化血红蛋白的照片如下 相同的BES协议。BES和BISED数据的比较不仅会 提供急需的发病和进展数据，但也会 允许风险因素评估和确定相对和 人口归因风险。基准风险因素数据包括 心血管变量、糖尿病和体型、眼部变量、使用 营养补充剂、药物暴露、吸烟和酗酒 使用、色素沉着、家族聚集性、遗传标记、人口统计学 和卫生保健利用措施。这些信息将提供 公共卫生规划、了解病因学、确定 高危人群和制定适当的战略以控制 视力丧失。BISED的可行性得到了初步研究的支持 94%的参与率和91%的积极回应 对退货检查的回应。

The Barbados Incidence Study of Eye Diseases (BISED) is designed to provide epidemiologic data on open-angle glaucoma (OAG) and other major causes of visual loss in black populations. It aims to determine incidence, progression and risk factors for OAG, age-related cataract, age-related macular degeneration, diabetic retinopathy and visual impairment among the population-based cohort of about 4500 persons, ages 40-86 years, who were examined from 1988-1992 as part of the Barbados Eye Study (BES). The BES was designed to measure prevalence and risk factors for each of the major eye diseases in a black population and to establish a baseline for future incidence measurements. No incidence or progression data have ever been collected on eye diseases in blacks that are based on a nationwide prevalence study with a high (85%) participation, a sufficiently large population to allow both precise estimates and risk factor assessment, and standardized and reproducible clinical and photographic protocols to measure each disease. To achieve these aims, BES participants would be re-examined to obtain ocular data (e.g., intraocular pressure, refraction, visual acuity, visual fields, lens gradings), blood pressure and anthropometric measurements, medical history and other interview data, stereo fundus photographs of the disc and macula and glycated hemoglobin, following the same BES protocol. Comparison of BES and BISED data would not only provide much needed data on incidence and progression, but would also allow risk factor evaluation and determination of relative and population attributable risks. Baseline risk factor data include cardiovascular variables, diabetes and body size, ocular variables, use of nutritional supplements, medication exposures, smoking and alcohol use, pigmentation, familial aggregation, genetic markers, demographic and health care utilization measures. The information will provide data for public health planning, understanding etiology, identifying groups at high risk and developing appropriate strategies to control visual loss. The feasibility of BISED was supported by a pilot study that had a 94% participation rate and a 91% positive response to a response to a return examination.