GYNECOLOGIC ONCOLOGY GROUP

这项提议是为了继续提供工作人员和 运营妇科肿瘤学小组(GOG)统计处， 合作研究小组。这个办公室的职能是 收集、提取、编码、更新、处理、分析和呈现数据 由成员机构提交。此外，谷歌统计数据 Office在设计、格式化和随机化方面发挥着重要作用 所有新方案，实施临时和最终研究主席审查， 是所有GOG摘要和 供出版的手稿。 谷歌统计局的一个主要目标是在即将到来的 授权期是随机化、表格跟踪、 将违法行为监测和医疗质量控制纳入GOG 统计局机制。这些任务以前由以下人员完成 Gog业务处，但已被重新分配到统计局 在最后一次现场访问和相应的批评之后。 我们的主要目标是以高效和 态度准确，分析及时，合乎逻辑，恰当 成果解释和相关出版物。取得的成就 这些目标将直接影响到未来的管理 妇科恶性肿瘤患者。 所涉及的方法包括： (A)GOG统计局参与研究设计的所有阶段， GOG议定书规定的行为、管理和口译 程序手册； (B)将随机化和质量控制程序纳入 GOG统计局业务； (C)扩大罗斯韦尔公园管理信息系统， 使用大型机版本的SIR实现表单跟踪和质量 对照； (D)继续扩大使用计算机评估表，其中包括 促进研究主席、数据抽象者和 统计学家；因此，每年对每项议定书进行两次彻底审查 解决问题并将意见或建议纳入 病人数据。 (E)协调、监测和编写政府间专家组的所有出版物。

This proposal is for continuation of funding required to staff and operate the Statistical Office of the Gynecologic Oncology Group (GOG), a cooperative research group. It is the function of this office to collect, abstract, code, update, process, analyze and present the data submitted by member institutions. Additionally, the GOG Statistical Office plays a major role in the design, formatting and randomization of all new protocols, implements interim and final study chairman's reviews, and is the focal point for the preparation of all GOG abstracts and manuscripts for publication. A primary objective of the GOG Statistical Office during the upcoming grant period is the smooth integration of randomization, forms tracking, delinquency monitoring, and modality quality control into the GOG Statistical Office mechanism. These tasks were previously accomplished by GOG Operations Office but have been reassigned to the Statistical Office following the last site visit and corresponding critique. Our principal objective is to manage patient data in an efficient and accurate manner, resulting in timely analyses, logical and appropriate interpretation of results and relevant publications. the achievement of these goals will have direct bearing upon the future management of patients with gynecologic malignancies. The methodology involved consists of: (a) Involvement of GOG Statistical Office in all phases of study design, conduct, management and interpretation as mandated by GOG Protocol Procedures Manual; (b) Incorporation of randomization and quality control procedures into the GOG Statistical Office operation; (c) Expansion of Roswell Park Management Information Systems (RPMIS), using main-frame version of SIR to implement forms tracking and quality control; (d) Continued expanded use of computer evaluation sheets (EVL's) which facilitates interaction among study chairman, data abstractor, and statistician; thus, each protocol is thoroughly reviewed twice-yearly in order to resolve questions and incorporate comments or suggestions into the patient data. (e) Coordination, monitoring and preparation of all GOG publications.