CLINICAL RESEARCH CENTER FOR SENILE DEMENTIA

我们老龄临床研究中心(ACRC)的这次更新反映了 精神病学和行为学系的持续承诺 斯坦福大学理工学院致力于阿尔茨海默病(AD)的研究。我们的 中心的重点是与AD患者的下降率相关的因素。 我们认为，研究诸如照顾者抑郁的角色等问题， 睡眠障碍，以及其他医疗和精神问题 AD患者的总体下降可能导致治疗干预 减少总体残疾、对机构护理和家庭的需求 困难重重。此外，我们觉得神经病理，神经化学， 活体神经成像和神经心理学研究及其相互关系 TO下降的速度可以描述AD的亚型，这可能导致 对病因学的洞察。这是一个“核心中心”，被定义为一个中心 它主要提供核心研究功能，而不是直接 资助大型研究项目。 主要核心包括： 1.行政核心 2.生物统计/数据管理核心 3.临床核心 4.评估核心，用于检查临床核心的AD患者 六个互补的视角： 4A.神经心理学 4B.神经成像核心 4C。休眠核心 4D。心理社会核心 4E。神经化学核心 4F。神经病理学核心

This renewal of our Aging Clinical Research Center (ACRC) reflects the continuing commitment of the Department of Psychiatry and Behavioral Sciences at Stanford to the study of Alzheimer's Disease (AD). Our Center focuses on factors associated with rate of decline in AD patients. We feel that examining issues such as the role of caregiver depression, sleep disorders, and other medical and psychiatric problems in the overall decline of AD patients may lead to treatment interventions that reduce overall disability, need for institutional care, and family hardship. Furthermore, we feel that neuropathological, neurochemical, in vivo neuroimaging, and neuropsychological studies and their relations to rate of decline could delineate subtypes of AD which could lead to insights into etiology. This is a "Core Center," defined as a Center that primarily provides Core research functions rather than directly funds large research projects. The main Cores are: 1. Administrative Core 2. Biostatistics/Data Management Core 3. Clinical Core 4. Assessment Cores, which examine the Clinical Core's AD patients from six complementary perspectives: 4a. Neuropsychology 4b. Neuroimaging Core 4c. Sleep Core 4d. Psychosocial Core 4e. Neurochemistry Core 4f. Neuropathology Core