GENETICS IN HYPERTENSION IN AFRICAN AMERICANS

与布里格姆妇女医院的研究人员合作， 这项研究将评估激素改变与肾脏疾病之间的关系。 血流对血管紧张素II的反应，钠敏感性，降低 尿激肽释放酶排泄，低血浆肾素活性，改变 红细胞离子转运和6-β羟皮质醇增加 与非裔美国人原发性高血压的关系。 的 上述表型与必需的 还将评估高血压。

In collaboration with investigators at Brigham and Women's Hospital, this study will evaluate the association between altered hormonal and renal blood flow response to angiotension II, sodium sensitivity, decreased urinary kalikrein excretion, low plasma renin activity, altered erythrocyte ion transport, and increased 6-beta hydroxycortisol production with essential hypertension in African-Americans. The possible genetic linkage of the above phenotypes with essential hypertension will also be evaluated.