STUDIES OF OCCUPATIONAL POPULATION EXPOSED TO CARCINOGENIC AGENTS

禽白血病/肉瘤病毒抗体的血清学研究 （ALSV）和网状内皮组织增生症病毒（REV）的体外研究， 已经完成了REV对人类细胞的感染性，结果 首次表明人类/人类细胞可以感染 这些病毒。 人体ALSV和REV整合检测实验 基因组正在进行中。 肺结核病例对照研究结果 肉类行业的癌症表明，屠夫，切肉工和人 在屠宰场的牲畜饲养场和屠宰/屠宰区工作的人， 即使在控制吸烟后，肺癌的风险也非常高。 接触生肉也是一个危险因素。 这些调查结果指出 病毒，如牛白血病病毒，可能负责。 包装和 包装肉类也与增加风险有关 阿尔伯克基超市工作人员尿液中粘康酸的含量 已完成，统计分析正在进行。 巴尔的摩和密苏里州工人队列的死亡率分析 （N= 36，000）在切肉机和家禽工会已经开始， 造血/淋巴系统肿瘤病例对照研究分析 肉类行业的制度。 对30，000多名家禽业工人进行了跟踪调查， 芝加哥养老基金的控制正在进行中，这也是一个生态 北方牛、禽、猪癌症死亡率研究 卡罗莱纳。 对澳大利亚喷雾者血清中TCDD水平的分析已经完成， 至于其他二恶荚及呋喃的分析工作仍在进行中。

The serological study of antibodies to avian leukosis/sarcoma viruses (ALSV) and reticuloendotheliosis viruses (REV), and the in vitro study of the infectivity of REV for human cells have been completed, and the results indicate for the first time that humans/human cells cab be infected with these viruses. Experiments for detecting integrated ALSV & REV in human genome are in progress. The results of the case-control study of lung cancer in the meat industry indicate that butchers, meatcutters and persons who worked in the stockyard and killing/dressing areas of abattoirs were at extremely high risk of lung cancer, even after controlling for smoking. Contact with raw meat was also a risk factor. These findings point to viruses such as bovine leukemia virus as possibly responsible. Packing and wrapping of meat was also associated with increased risk Chemical analysis of urine for muconic acid in supermarket workers in Albuquerque is complete, and statistical analysis is in progress. Mortality analyses of the Baltimore and Missouri cohorts of workers (N=36,000) in a meatcutter and poultry unions has commenced, as is also analysis of a case-control study of tumors of the hemopoietic/lymphatic systems in the meat industry. Follow-up of over 30,000 poultry workers and controls in a Chicago Pension Fund is in progress, as is also an ecologic study of cancer mortality by cattle, poultry and pig inventory in North Carolina. Analysis of serum levels of TCDD in Australian sprayers is complete, while analyses of other dioxins and furans are in progress.