NEUROPHYSIOLOGY/PSYCHOLOGY IN MENTAL RETARDATION

这项建议的目的是在基础和临床方面进行研究 神经生理学、神经解剖学和神经心理学的相关方面 加深对精神发育迟滞及其相关方面的理解 人的发展。这一目标将通过利用人才来实现 以合作和协作的方式交流研究人员的意见。 该小组成员将承担以下任务： 1.行为学、电生理学和形态学的应用 动物正常发育和变化研究中的技术 在正常发育中，由于新生儿大脑的侮辱或 环境操纵。这些研究旨在阐明 运动功能减退的神经基础和提供动物模型 精神发育迟滞的物种。 2.正常和异常方面的机制研究 学习，包括研究塑料的细胞基础 在可能的情况下，细胞膜生理学的行为和相关性 超微结构分析。在一个新的项目中，研究了 本课程将介绍培养的中枢神经系统神经元中的突触。 3.在人类受试者和动物身上进行的平行研究 正常人和异常者听觉信息加工的研究 大脑具有了解异常本质的远景目标 弱智人类的听觉处理。 4.提供吸引和培养青年科学家的环境 在相关研究领域。

The aim of this proposal is to pursue research in basic and clinical aspects of neurophysiology, neuroanatomy, and neuropsychology relevant to an increased understanding of mental retardation and related aspects of human development. This aim will be implemented by utilizing the talents of researchers in a cooperative and collaborative manner. Members of this group will undertake the following tasks: 1. The application of behavioral, electrophysiological and morphological techniques in studies of normal development in animals and of alterations in normal development as a consequence of neonatal brain insult or environmental manipulation. These studies are designed to elucidate the neural bases of impaired performance and to provide animal models of species of mental retardation. 2. A study of the mechanisms underlying normal and abnormal aspects of learning, including investigations of the cellular bases of plastic behavior and, where possible, correlation of cell membrane physiology with ultrastructural analysis. In a new project, studies of the development of synapses in cultured CNS neurons will be addressed. 3. Parallel studies in human subjects and in animals designed to investigate auditory information processing in the normal and abnormal brain with the long-range goal of understanding the nature of abnormal auditory processing in the retarded human. 4. The provision of a milieu for attracting and training young scientists in related research areas.