EFFECTS OF PROGESTERONE ON CEH IN THE SLA INBRED MINIATURE PIG

SLA近交系小型猪群，由 NCI免疫学分支的有蹄类单位通常生产 一窝小崽，表现出各种生殖问题， 在标准体型的猪身上发现的 子宫的状况，囊性的 子宫内膜增生症（CEH），存在于牛群中， 降低了畜群的繁殖效率。 一岁以后才繁殖的母猪， CEH的发病率和不能生育。 回归 或降低CEH的发生率将大大改善 畜群的繁殖性能。 先前的研究 显示SLA近交系小型猪的血清孕酮 比标准尺寸的猪低很多。 的影响 孕激素长期给药对CEH将是 研究了

The SLA inbred miniature pig herd, bred and maintained by the Ungulate Unit for the Immunology Branch, NCI typically produces a small litter and exhibits a variety of reproductive problems not found in the standard-sized pig. A uterine condition, cystic endometrial hyperplasia (CEH), exists in the herd and is directly involved in reducing the reproductive efficiency of the herd. Sows that are not bred until after one year of age have a high incidence of CEH and are incapable of reproduction. Regression or reduction of the incidence of CEH would improve greatly the reproductive performance of the herd. Previous studies have showed the SLA inbred miniature pig has a serum progesterone level considerably lower than the standard-sized pig. The effects of long term administration of progesterone on CEH will be studied.