Midland Hub for Trials Methodology Research at University of Birmingham

临床试验测试潜在的人类治疗方法，看看它们是否应该被批准在普通人群中更广泛地使用。任何新的治疗方法都必须经过广泛的测试，以确保它对患者有益、安全、没有不可接受的副作用。大多数情况下，治疗方法是药物，但也可以是医疗设备、外科手术或物理手术、治疗或健康促进等干预措施。志愿者被招募到临床试验中接受新的治疗，通常试验中会包括一组只接受标准治疗的人。通过这种方式，可以将患者接受新治疗的结果与标准治疗进行比较，看看它是否有益。计划如何进行试验，并确保它解决了正确的问题，这对于确保试验的结果是有用的很重要。对试验中收集的数据的解释也需要保证得出有效的结论。这项研究的计划是在伯明翰大学建立一个区域机构，研究设计、实施和分析试验的最佳方法，为进行试验的人员和公众提供建议、支持和培训。最终，这将导致更有效地向患者提供有益的治疗。

Clinical trials test potential treatments in humans to see if they should be approved for wider use in the general population. Any new treatment must be extensively tested to check that it benefits patients, is safe and doesn t have unacceptable side effects. Most often the treatment is a drug, but it could be a medical device, a surgical or physical procedure, a therapy or an intervention such as health promotion. Volunteers are recruited into the clinical trial to undergo the new treatment and usually the trial will include a group who just receive the standard treatment. In this way, the outcome of patients on the new treatment can be compared to the standard to see if it is beneficial. Planning how the trial will be run and making sure it addresses the right questions are important to ensure that the results from the trial will be useful. Interpreting the data that is collected in the trial also needs to guarantee that valid conclusions are reached. The plan for this research is to create a regional facility at the University of Birmingham in which to investigate the best ways to design, conduct and analyse trials, providing advice, support and training to those carrying out trials and to the public. Ultimately this will result in beneficial treatments being delivered to patients more efficiently.