Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) - Network Clinical Center (Hub)

紧急护理临床试验网络：紧急护理临床试验网络 (SIREN) 的创新策略 - 网络临床中心（中心）

• 批准号: 10622025
• 负责人: Michelle Helen Biros
• 金额: $ 7.75万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10622025
• 关键词: Accident and Emergency department; Ambulances; Ancillary Study; Award; COVID-19 pandemic; Clinical Trials; Clinical Trials Network; Consent; Critical Care; Emergency Care; Emergency Situation; Emergency research; Emergency treatment; Enrollment; Ensure; Funding; Height; Individual; Institution; Intensive Care Units; Location; Medical emergency; Minnesota; Multi-Institutional Clinical Trial; Nature; Participant; Patient Care; Patient Recruitments; Performance; Preparation; Research; Research Activity; Research Subjects; Research Support; Science; Structure; Time; Universities; Work; base; clinical center; cost; emergency settings; experience; improved; injured; innovation; operation; participant enrollment; recruit; skills; treatment trial

Project Summary and Abstract This supplement requests support of key activities and effort for key individuals that will allow the University of Minnesota SIREN Hub to continue operations for recruiting participants into emergency care research. Supplemental support is requested to maintain operations between the end of regular funding for the first 5 years of SIREN and start of the second 5 years of SIREN. Uninterrupted support of the Minnesota Hub will ensure successful enrollment of participants into the ongoing SIREN trials (ICECAP, BOOST-3, and HOBIT), and the continued support for the ancillary studies for these trials (Bio-BOOST to start soon, and Bio- HOBIT). During the height of the COVID pandemic, SIREN research activities were paused or severely limited at our Hub institutions and Spokes, and enrollment options (and accompanying funds to support research teams) were often unavailable, despite continued Hub financial needs. We therefore anticipate ending the current SIREN funding cycle with a deficit, which we will cover with funding from the Dean’s office and some departmental funds. These internal funds are very limited, however, and are not available to cover the cost of the continuation of our work until the next SIREN funding cycle. Thus, the supplement funds being requested will be essential for uninterrupted Minnesota Hub performance.

项目概要和摘要 本补充要求对关键个人的关键活动和努力提供支持，使大学能够 明尼苏达州 SIREN 中心将继续运营，招募参与者参与紧急护理研究。 请求补充支持以维持前 5 个项目常规资助结束期间的运营 SIREN 年以及 SIREN 第二个 5 年的开始。明尼苏达中心的不间断支持将 确保参与者成功加入正在进行的 SIREN 试验（ICECAP、BOOST-3 和 HOBIT）， 以及对这些试验的辅助研究的持续支持（即将启动的 Bio-BOOST 和 Bio-HOBIT）。 在新冠肺炎疫情最严重期间，SIREN 的研究活动暂停或受到严格限制。 中心机构和辐条以及注册选项（以及支持研究团队的附带资金） 尽管中心持续存在财务需求，但经常无法使用。因此，我们预计结束当前的 SIRN 资金周期有赤字，我们将用院长办公室和一些机构的资金来弥补 部门资金。然而，这些内部资金非常有限，无法用于支付费用。 我们的工作将持续到下一个 SIRN 资助周期。因此，要求补充资金 对于不间断的明尼苏达枢纽性能至关重要。