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The Centre for Neuropsychiatric Genetics and Genomics

The Centre for Neuropsychiatric Genetics and Genomics
神经精神遗传学和基因组学中心
批准号:
G0801418/1
负责人:
Michael Owen
金额:
$317.68万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2009
资助国家:
英国
项目状态:
已结题
起止时间:
2009 至 --

项目摘要

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中文摘要
翻译
该中心的目标是了解导致精神障碍和痴呆症的一系列常见原因的遗传学,并利用这种了解改进对这些疾病的诊断和治疗。基因在精神分裂症、双相情感障碍、抑郁症、注意力缺陷障碍、阿尔茨海默病和帕金森病等疾病中发挥着重要作用。这些常见疾病的遗传学是复杂的,很可能涉及许多基因。然而,使用现代基因方法,现在可以开始识别常见疾病背后的特定基因异常。S中心未来5年的使命核心将是继续致力于识别所有上述疾病的基因。然而,人们将越来越重视利用所获得的知识,通过改善对疾病机制的理解、更好的诊断以及最终开发新的治疗方法来造福患者。
英文摘要
The goal of the Centre is to understand the genetics of a range of common causes of psychiatric disorders and dementia and to use this understanding to improve the diagnosis and treatment of these disorders. Genes play an important role in disorders such as schizophrenia, bipolar disorder, depression, attention deficit disorder, Alzheimer disease and Parkinson disease. The genetics of these common disorders is complex and it is likely that many genes are involved. However, using modern genetic methods it is now possible to begin to identify the specific genetic abnormalities that underlie common diseases. The core of the Centre?s mission over the next 5 years will be to continue work aimed at identifying genes underlying all of the above disorders. However, there will be an increasing emphasis upon using the knowledge gained to benefit patients via improved understanding of disease mechanisms, better diagnosis and ultimately the development of new treatments.
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Molecular Genetic Studies of Schizophrenia
  • 批准号:
    MR/P005748/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $306.71万
  • 财政年份:
    2016
  • 负责人:
    Michael Owen
  • 依托单位:
MRC Centre for Neuropsychiatric Genetics and Genomics
  • 批准号:
    MR/L010305/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $237.86万
  • 财政年份:
    2014
  • 负责人:
    Michael Owen
  • 依托单位:
Molecular Genetics of Schizophrenia
  • 批准号:
    G0800509-E01/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $298.4万
  • 财政年份:
    2011
  • 负责人:
    Michael Owen
  • 依托单位:
Molecular Genetics of Schizophrenia
  • 批准号:
    G0800509/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $214.93万
  • 财政年份:
    2008
  • 负责人:
    Michael Owen
  • 依托单位:
海外基金