MRC Centre for Reproductive Health

繁殖是所有生命的基本特征，对我们物种的延续至关重要。一个健康婴儿的诞生标志着一系列非凡事件的高潮，也是我们迈向长寿健康生活的决定性时刻。生殖组织为我们的生育提供了平台，并培育了成功的怀孕，其特点是具有非凡的韧性？？即他们承受挑战或迅速从挑战中恢复的能力？否则可能会对它们的功能产生不利影响。其他组织通常不会表现出这样的韧性。我们的新中心将把研究生殖组织再生、修复和更新方式的科学家与专注于脑、肝、肺和肾的干细胞生物学、组织再生、炎症和胎儿发育研究的医生和科学家团队联系起来，使他们能够承受现代生活方式的影响，包括压力和肥胖。这种多学科的方法将确保我们可以将我们的研究成果应用于开发针对常见生殖问题的新疗法，如不孕不育、月经过多、早产、低出生体重，并将其应用于影响肝、脑、肺和血管系统的疾病的治疗，如肝硬变和癌症。至关重要的是，我们将通过我们的公开讲座和学校推广计划，培训下一代基础和临床科学家，了解生殖医学及其更广泛的应用，并向公众宣传我们新的令人兴奋的研究成果。

Reproduction is a fundamental feature of all life, essential for the continuation of our species. The birth of a healthy baby represents the culmination of a remarkable series of events and a defining moment in our progress towards ?living a long and healthy life?. The reproductive tissues that provide the platform for our fertility and nurture a successful pregnancy are characterised by their remarkable ?resilience? ? namely their ability to withstand or recover quickly from ?challenges? that might otherwise have an adverse impact on their function. Other tissues cannot usually show such resilience. Our new Centre will link scientists studying the ways in which reproductive tissues regenerate, repair and renew themselves enabling them to withstand the impacts of our modern lifestyle including stress and obesity, with teams of doctors and scientists who are focusing their research on stem cell biology, tissue regeneration, inflammation and fetal growth in the brain, liver, lung and kidney. This multidisciplinary approach will ensure we can apply our research findings to the development of new therapies for common reproductive problems such as infertility, heavy periods, premature birth, low birth weight, but also that they are applied towards therapies for diseases that affect the liver, brain, lung and vascular system such as cirrhosis and cancer. Crucially, we will train the next generation of basic and clinician scientists in reproductive medicine and its broader exploitation and communicate our new and exciting research findings to the general public, through our public lecture and schools outreach programmes.