Dissecting roles of High Mobility Group A1 (HMGA1) pathway in pancreatic adenocarcinoma progression through in vivo monitoring of cancer dynamics...

胰腺癌是人类癌症中最致命的。这种癌症迫切需要有效的治疗和早期发现策略。我们的项目旨在了解胰腺癌的进展过程，希望找到治疗和检测这种癌症的新方法。通过关注高迁移率A1 （HMGA1）基因的作用，我们可能找到合理治疗胰腺癌的新途径。我们的项目可能会导致基于成像的早期检测策略的发展。

Pancreatic cancer is the deadliest of human cancers. Effective treatment and early detection strategies for this cancer is desperately needed. Our project aims to understand the process of pancreatic cancer progression, in the hope of identifying new ways to treat and detect this cancer. By focussing on the roles of high mobility group A1 (HMGA1) gene, we may identify novel pathways for rational therapy of pancreatic cancer. Our project may lead to the development of imaging-based early detection strategies.