COMPUTER PROGRAMS FOR ANALYSIS OF LABORATORY AND CLINICAL DATA

这个实验室延续了开发新型计算机的传统 临床和实验室数据分析程序。 我们已经开发 用于分析人的偶发性激素分泌的多种新方法， 实验动物和体外灌流细胞系统。 这些 方法具有统计学有效性、客观性、可靠性、灵敏度和产率 新的生理信息，包括激素的瞬时速率 分泌和激素代谢的半衰期或衰减常数 和退化。 其他方案包括改进的方法， 酶-底物-抑制剂的Lineweaver-Burk和Dixon作图分析 系统、放射免疫测定、生物测定、放射受体测定、X射线 失活和解离研究。

This laboratory continues its tradition of developing novel computer programs for analysis of clinical and laboratory data. We have developed multiple new approaches for analysis of episodic hormone secretion in man, experimental animals, and in in vitro perifused cell systems. These methods are statistically valid, objective, reliable, sensitive and yield new physiological information including the instantaneous rate of hormone secretion and the half-life or decay constant(s) for hormone metabolism and degradation. Other programs include improved methods for Lineweaver-Burk and Dixon-plot analysis of enzyme-substrate-inhibitor systems, radioimmunoassays, bioassays, radio receptor assays, X-ray inactivation and dissociation studies.