Programme 3: Early development and risk of adult musculoskeletal disease

该方案的目的是将观察流行病学和机制理解结合起来，为早期生活提供新的干预措施，以减少后来发生骨质疏松症和骨质疏松症等疾病的风险。虽然我们的结果已经为国家指南(卫生部、NICE、英国公共卫生和营养科学咨询委员会)提供了信息，但该方案将通过产生发现科学来推进这项工作，以描绘潜在的机制并建立这些发现的更广泛的相关性，以便为最终的公共卫生战略的成功实施提供信息。

The aim of this programme is to integrate observational epidemiology and mechanistic understanding to inform novel interventions in early life to reduce the risk of later diseases such as osteoporosis and sarcopenia. Whilst our results have already informed national guidelines (DH, NICE, Public Health England and the Scientific Advisory Committee on Nutrition), the programme will advance this work by generating discovery science to delineate underlying mechanisms and to establish the wider relevance of the findings in order to inform the successful implementation of resulting public health strategies.