Mary Lyon Centre, International Facility for Mouse Genetics, at MRC Harwell
Mary Lyon Centre, International Facility for Mouse Genetics, at MRC Harwell
批准号:
MC_UP_2201/1
负责人:
Sara Wells
金额:
$3713.67万
依托单位:
依托单位国家:
英国
项目类别:
Intramural
财政年份:
2022
资助国家:
英国
项目状态:
未结题
起止时间:
2022 至 --
中文摘要
Harwell医学研究中心(MLC)的玛丽·里昂中心是英国研究小鼠遗传学和使用小鼠模型研究人类疾病的国家机构。为英国研究人员提供的专业服务包括转基因小鼠的产生和研究,以及国家小鼠档案馆,该档案馆允许科学家免费存放小鼠品系,用于存档和分发目的。MLC也是MRC国家小鼠遗传学网络的中心枢纽,该网络汇集了来自英国各地的专家,以合作和共享资源。
英文摘要
The Mary Lyon Centre at MRC Harwell (MLC) is the UK’s national facility for mouse genetics and the use of mouse models for the study of human disease. The specialised services available for UK researchers include the generation and study of genetically altered mice, and the National Mouse Archive, which allows scientists to deposit mouse strains free of charge for archiving and distribution purposes. The MLC is also the central hub of the MRC National Mouse Genetics Network which brings together experts from around the UK to collaborate and share resources.
期刊论文(10)
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Hypercalcaemic mice harbouring a germline ablation of G-protein subunit alpha-11 have anaemia that is corrected by treatment with erythropoietin
携带 G 蛋白亚基 α-11 种系消融的高钙血症小鼠患有贫血,可通过促红细胞生成素治疗来纠正
DOI:
10.1530/endoabs.86.oc1.2
发表时间:
2022
期刊:
Endocrine Abstracts
影响因子:
--
作者:
[Hannan F]
通讯作者:
Hannan F
Presenting the genotyping services at the Mary Lyon Centre at MRC Harwell; a high-throughput mouse genotyping pipeline
在 MRC Harwell 的玛丽里昂中心展示基因分型服务;
DOI:
--
发表时间:
2022
期刊:
Transgenic Research
影响因子:
3
作者:
[Caulder A]
通讯作者:
Caulder A
DOI:
10.1186/s12915-022-01475-0
发表时间:
2023-02-03
期刊:
BMC BIOLOGY
影响因子:
5.4
作者:
[Chee, Justine, Lanoue, Louise, Clary, Dave L., Higgins, Kendall, Bower, Lynette, Flenniken, Ann, Guo, Ruolin, Adams, David, Bosch, Fatima, Braun, Robert E., Brown, Steve D. M., Chin, H. -J. Genie, Dickinson, Mary, Hsu, Chih-Wei, Dobbie, Michael, Gao, Xiang, Galande, Sanjeev, Grobler, Anne, Heaney, Jason, Herault, Yann, de Angelis, Martin Hrabe, Mammano, Fabio, Nutter, Lauryl M. J., Parkinson, Helen, Qin, Chuan, Shiroishi, Toshi, Sedlacek, Radislav, Seong, J-K, Xu, Ying, Brooks, Brian, McKerlie, Colin, Lloyd, K. C. Kent, Westerberg, Henrik, Moshiri, Ala]
通讯作者:
Moshiri, Ala
DOI:
10.1186/s13073-022-01118-7
发表时间:
2022-10-13
期刊:
Genome medicine
影响因子:
12.3
作者:
[]
通讯作者:
TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system.
TMEM161B 调节发育中的中枢神经系统中的大脑皮质回旋、Sonic Hedgehog 信号传导和纤毛结构。
DOI:
10.1073/pnas.2209964120
发表时间:
2023-01-24
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子:
11.1
作者:
[Akula, Shyam K., Marciano, Jack H., Lim, Youngshin, Exposito-Alonso, David, Hylton, Norma K., Hwang, Grace H., Neil, Jennifer E., Dominado, Nicole, Bunton-Stasyshyn, Rosie K., Song, Janet H. T., Talukdar, Maya, Schmid, Aloisia, Teboul, Lydia, Mo, Alisa, Shin, Taehwan, Finander, Benjamin, Beck, Samantha G., Yeh, Rebecca C., Otani, Aoi, Qian, Xuyu, DeGennaro, Ellen M., Alkuraya, Fowzan S., Maddirevula, Sateesh, Cascino, Gregory D., Giannini, Caterina, Undiagnosed Diseases Network, Lindsay C., Burrage, Lindsay C., Rosenfield, Jill A., Ketkar, Shamika, Clark, Gary D., Bacino, Carlos, Lewis, Richard A., Segal, Rosalind A., Bazan, J. Fernando, Smith, Kelly A., Golden, Jeffrey A., Cho, Ginam, Walsh, Christopher A.]
通讯作者:
Walsh, Christopher A.
共 7 条
Multiplex biomarker assay reader- Purchase of Electrochemiluminescence Reader under the MRC Equipment bid
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批准号:MR/X012492/1
-
项目类别:Research Grant
-
资助金额:$16.89万
-
财政年份:2022
-
负责人:Sara Wells
-
依托单位:
MLC National Mouse Genetics Network
-
批准号:MC_PC_21047
-
项目类别:Intramural
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资助金额:$583.93万
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财政年份:2022
-
负责人:Sara Wells
-
依托单位:
海外基金