Enabling technologies

使能技术方案由一些核心设施组成，这些设施向MDU的科学家提供关键技术和设备，它的成功至关重要。由于代谢性疾病影响全身，因此对这些疾病进行整体动物研究是至关重要的。我们选择的模型是鼠标。疾病模型核心提供了测量动物体内脂肪和肌肉的数量，吃了多少和什么类型的食物，以及通过新陈代谢、产热或锻炼燃烧了多少能量的设施。它还提供了检查分离的细胞、组织和器官的设施。在尺寸谱的另一端，基因组学/转录学核心使科学家能够研究基因的亚微观世界，以及它们如何功能并转化为蛋白质，核心生化分析实验室测量血液中的荷尔蒙和其他分子。

The Enabling Technologies programme consists of a number of core facilities that provide critical technologies and equipment to scientists in the MDU and it is crucial its success. Because metabolic disease affects the entire body, it is vital to study these diseases whole animals. Our model of choice is the mouse. The Disease Model Core provides facilities for the measurement of the amount of fat and muscle in an animal’s body, how much and what type of food is eaten, and how much energy is burnt, through either metabolism, heat production, or exercise. It also provides facilities for examining isolated cells, tissues and organs. At the other end of the size spectrum, the Genomics/Transcriptomics Core enables scientists to study the sub-microscopic world of genes and how they function and are turned into proteins and the Core Biochemistry Assay Lab measures hormones and other molecules in blood.