Developing and evaluating a multimodal antibiotic allergy strategy to improve antimicrobial stewardship in high-risk antibiotic usage populations

抗生素过敏会导致使用劣质抗生素，并产生“超级细菌”。抗生素过敏测试可以消除高达90%的过敏，尽管许多人仍然无法获得，在一些严重的抗生素反应中也不可靠。我们的目标是验证抗生素过敏床边工具和程序，并开发能够诊断和预防严重抗生素过敏的实验室测试，以改善适当的抗生素处方和患者结果。

Antibiotic allergies lead to the use of inferior antibiotics and generation of “superbugs”. Antibiotic allergy testing removes up to 90% of allergies, although remains unavailable to many and unreliable in some severe antibiotic reactions. We aim to validate antibiotic allergy bedside tools and programs, and develop laboratory tests that can diagnose and prevent severe antibiotic allergies, to improve appropriate antibiotic prescribing and patient outcomes.