INVESTIGATION OF BETA ADRENERGIC RECEPTOR--ASTHMATIC SUBJECTS

在这项研究中，将少量抗原滴入 24或48小时后，细胞和可溶性介质 将通过支气管肺泡灌洗从同一节段取样。 将通过刷拭获得上皮细胞。 相同的程序 将在另一边的另一个实验室进行， 控制 本研究将在健康受试者和 过敏性哮喘患者。 这项研究与 哮喘的发病机制。

In this investigation, a small amount of antigen will be instilled into segmental bronchus and after 24 or 48 hours, cells and soluble mediators will be sampled from the same segment by bronchoalveolar lavage. Epithelial cells will be obtained by brushing. The same procedure without the antigen will be done in another lab on the opposite side as control. This study will be performed in healthy subjects and in patients with allergic asthma. This study is relevant to the pathogenesis of asthma.