VENOGLOBULIN-I(10%) FOR STEROID DEPENDENT ASTHMA AND ATOPIC DERMATITIS

Mazer & Gelfand报告说， 4岁时接受大剂量IVIG的激素依赖性哮喘儿童 每周间隔，关于所需的类固醇量，皮肤试验 反应性和肺功能测试。此外，Greenberg等人 在皮炎和降低血清中显示出实质性的改善 免疫球蛋白治疗重症特应性皮炎的IgE反应 这 临床试验旨在证实和扩展初步研究 使用更浓缩形式的IVIg。

Mazer & Gelfand have reported substantial improvement in eight steroid-dependent asthmatic children receiving high dose IVIG at four week intervals, with regard to amount of steroid required, skin test reactivity & pulmonary function tests. Also, Greenberg et al. have demonstrated a substantial improvement in dermatitis & decrease in serum IgE in response to IVIG treatment for severe atopic dermatitis. This clinical trial is designed to confirm and extend the preliminary studies outlined above using a more concentrated form of IVIg.