Developing robust biomarkers for vascular cognitive impairment and dementia: Adding V to the ATN research framework

本研究的主要目的是开发血管性痴呆的生物标志物。它建立在我领导的纵向研究和国际财团的基础上。这些研究将使用多模式磁共振成像、先进的视网膜成像、质谱仪和其他技术来建立和验证血管对痴呆症的贡献的强大生物标志物。这一发现将有助于实现对血管性痴呆的明确诊断，并量化痴呆症患者的血管病理。

The main objective of this research is to develop biomarkers for vascular dementia. It builds upon the longitudinal studies and international consortia that I lead. The studies will use multimodal MRI, advanced retinal imaging, mass spectrometry and other techniques to establish and validate robust biomarkers of vascular contributions to dementia. The findings will help achieve a definitive diagnosis of vascular dementia and quantify vascular pathology in someone with dementia.