INTERNAL VERSUS EXTERNAL SENSING FOR ROTARY BLOOD PUMPS

描述（改编自申请人摘要）：第一阶段的主要目标是 比较内部传感器与外部传感器的有效性， 旋转血泵的状态监测。这个问题的基本假设 建议是直接安装在血泵上的振动传感器将 以良好的可重复性和高灵敏度检测早期故障， 的特异性该假设将通过使用植入的 加速度计和外部麦克风，以记录来自 动物植入式振动发生器这种方法将提供信息 类似于种子断层实验。信号频率的各种混合， 代表不同失效模式的强度将使用 振动发生器，来自加速度计和麦克风的信号将被 分析以量化传感器的灵敏度和特异性以及 活组织对信号传输和阻尼影响。这些信息将 不仅有助于为第二阶段的工作做出明智的决定， 开发一个状态监测系统，但也将是重要的 开发用于类似心脏假体的监测系统。 拟议商业应用：不可用

DESCRIPTION (Adapted from applicant's abstract): The main goal of Phase I is to compare the effectiveness of internal sensors versus external sensors for condition monitoring of rotary blood pumps. The fundamental hypothesis of this proposal is that a vibration sensor mounted directly on the blood pump would detect incipient failures with good repeatability, high sensitivity, and specificity. This hypothesis is to be evaluated by using an implanted accelerometer and external microphone to record signals from an animal-implanted vibration generator. This approach will provide information similar to seeded-fault experiments. Various mixes of signal frequencies and strengths representing different failure modes will be introduced using the vibration generator, and signals from the accelerometer and microphone will be analyzed to quantify sensitivity and specificity of sensors as well as the effect of live tissue on signal transmission and damping. This information will not only help in making informed decisions for a Phase II effort for development of a condition monitoring system, but will also be important for development of monitoring systems for similar cardiac prostheses. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE