ENDOSCOPIC TREATMENT FOR ULCER BLEEDING (USING CORI)

内窥镜治疗非出血可见血管(NBVV)溃疡的有效性在美国各地尚未在多个实践环境中进行研究。美国胃肠内窥镜协会(ASGE)-临床结果研究倡议(CORI)项目-是一个由胃肠专家组成的全国性联盟，利用计算机化的内窥镜数据库收集内窥镜数据，以研究内窥镜检查的结果。这项试点/可行性研究的主要目的是证明一个国家临床从业者联盟收集有效性数据的能力，将两种内窥镜治疗溃疡与NBVV进行比较。双极电凝(BP)的有效性和安全性将与注射肾上腺素后双极电凝(BP/E)进行比较。通过合并和测试试验数据收集，这将允许扩展多中心研究中的数据收集，该研究涉及在各种实践环境中的多个地理地点的执业医生。这项研究的一个独特之处在于，它是第一个在全美多个实践地点进行的上消化道出血(UGIB)有效性和安全性研究。数据将在16个地点输入，并以电子方式传输进行分析。通过实施这项试点研究来测试扩展的数据库结构，将为更大规模的研究奠定基础，在该研究中，将利用CORI数据收集基础设施调查临床、安全性和经济学结果。

The effectiveness of endoscopic therapy for ulcers with non-bleeding visible vessels (NBVV) has not been studied in multiple practice settings throughout the United States. The American Society for Gastrointestinal Endoscopy (ASGE) - Clinical Outcomes Research Initiative (CORI) Project - is a national consortium of gastrointestinal specialists that collects endoscopic data utilizing a computerized endoscopic database to study outcomes in endoscopy. THE PRIMARY AIM OF THIS PILOT/FEASIBILITY STUDY IS TO DEMONSTRATE THE ABILITY OF A NATIONAL CONSORTIUM OF CLINICAL PRACTITIONERS TO COLLECT EFFECTIVENESS DATA COMPARING TWO ENDOSCOPIC TREATMENTS FOR ULCERS WITH NBVV. The efficacy and safety of bipolar coagulation (BP) alone will be compared to bipolar coagulation after injection with epinephrine (BP/E). By incorporating and testing trial data collection this will permit the expansion of data collection in a multicenter study involving practicing physicians in multiple geographic sites in a variety o practice settings. A unique aspect of this study is that it is the first effectiveness and safety study of upper gastrointestinal bleeding (UGIB) performed in multiple practice sites across the United States. Data will be entered at 16 sites and transmitted electronically for analysis. By testing the expanded database structure by implementing this pilot study, the groundwork will be lain for a larger study in which clinical, safety, and economic outcomes will be investigated making use of the CORI data collection infrastructure.