COGNITIVE EVOKED POTENTIALS IN DROWSINESS & SLEEP ONSET

描述（改编自申请人的摘要）：一种基于计算机的系统， 提出将使用认知事件相关电位（ERP）来评估 困倦状态和检测睡眠开始。它将把联合收割机ERP与计算机化的 多导睡眠图（PSG），以提供客观的状态变化的措施， 睡眠实验室和研究应用。第一阶段将用于确定 最能反映困倦和嗜睡之间差异的ERP成分， 警觉性，以及成年人的清醒和睡眠之间，没有睡眠相关的 问题这些受试者将在清醒和睡眠时进行研究 一无所有还将对患有阻塞性睡眠的患者进行记录 呼吸暂停（OSA），以确定可能出现在个人的技术问题 睡眠和清醒模式紊乱该项目的目标是 生产设备：1）ERP睡眠研究; 2）临床研究， 睡眠实验室（用于客观评估白天嗜睡和睡眠质量） 信息处理和用于检测睡眠开始）; 3）家庭 (e.g.,用于跟踪治疗效果）。为这些 目的，ERP具有重要的优势，他们可以索引的认知 大脑的状态，即使在睡眠中，也不需要行为， 扰乱状态的变化。 拟议商业应用：不可用

DESCRIPTION (Adapted from applicant's abstract): A computer-based system is proposed that will use cognitive event-related potentials (ERPs) to assess the drowsy state and to detect sleep onset. It will combine ERPs with computerized polysomnography (PSG) to provide objective measures of state changes for both sleep-laboratory and research applications. Phase I will be used to determine the ERP components that best reflect differences between drowsiness and alertness, and between waking and sleeping in adults with no sleep-related problems. These subjects will be studied both when alert and when sleep deprived. Recordings will also be made from patients with Obstructive Sleep Apnea (OSA), to define the technical problems that might arise in individuals with disordered waking and sleeping patterns. The goal of the project is to produce equipment for: 1) ERP research on sleep; 2) clinical studies in the sleep lab (for the objective assessment of daytime sleepiness and quality of information processing and for the detection of sleep onset); 3) the home (e.g., for follow-up of treatment effects) using a portable version. For these purposes, ERPs have the important advantage that they can index the cognitive state of the brain, even in sleep, without requiring behaviors that would perturb changes in state. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE