CORE--PERIPHERAL STEM CELL LABORATORY

外周干细胞核心实验室的主要职能将是 作为重建造血过程的管道 从人骨中分离、提纯和/或扩增的干细胞 骨髓、外周血或胎盘血。这个中央核心实验室将 确保所有干细胞材料分发到 用于研究目的的其他实验室，遵守所有当前和 未来对所有项目的监管要求和成本控制，批量 中央采购协议和由高效和综合 供应品的利用。外周干细胞核心实验室(SCL) 将有两个互动的复合体，i)Apheresis单位收集 正常供者和患者外周血干细胞(PBSC)和 Ii)外周干细胞研究实验室。分离服务 包括从患者身上收集外周血干细胞， 异基因单个供者血小板和外周血干的采集 用于研究目的的细胞来自正常的志愿者捐赠者。服务对象 由外周干细胞研究实验室提供，包括： 一)干细胞群体的分离、纯化和体外扩增 骨髓、外周血和胎盘血，II)干细胞分析 用流式细胞术和免疫组织化学方法检测种群，III) 用于研究的干细胞种群的超低温保存和存储， 四)支付纯化、扩增和/或冷冻保存的干细胞 用于研究的人口和v)发展和实施 基因转移到造血干细胞的临床方案 人口。

The primary function of the Peripheral Stem Cell Core Laboratory will be to act as the conduit for the processing of reconstituting hematopoietic stem cells, isolated, purified and/or expanded from either human bone marrow, peripheral or placental blood. This central core laboratory will ensure the quality control of all stem cell materials distributed to other laboratories for research purposes, adherence to all current and future regulatory requirements and cost control for all projects, by bulk central purchasing agreements and by the efficient and integrated utilization of supplies. The Peripheral Stem Cell Core Laboratory (SCL) will have two interactive compounds, i) the Apheresis Unit to collect peripheral blood stem cells (PBSC) from normal donors and patients and ii) the Peripheral Stem Cell Research Laboratory. Apheresis services include the collection of peripheral blood stem cells from patients, the collection of allogeneic single donor platelets and peripheral blood stem cells for research purposes from normal volunteer donors. Services to be provided in the Peripheral Stem Cell Research Laboratory, include: i) Isolation, purification and ex-vivo expansion of stem cell populations from marrow, peripheral and placental blood, ii) Analysis of stem cell populations by flow cytometry and immunohistochemistry, iii) Cryopreservation and storage of stem cell populations for research use, iv) Disbursement of purified, expanded and/or cryopreserved stem cell populations for research purposes and v) Development and implementation of clinical protocols for gene transfer into hematopoietic stem cell populations.