CORE--CLINICAL

临床研究核心的目标是完成有意义的 临床调查研究，同时整合 最高质量的“最先进的”病人护理。 的功能 核心将是提供临床，技术专长和适当的 设施，以帮助实施该计划的三个临床协议 项目 许多测试、调查和数据收集将 发生在病人最不稳定，最需要照顾的时候。 必需的. 这个核心集中了调查小组， 全年24小时待命，并提供必要的专业知识 开展脑微透析、脑血 脑血流、磁共振脑水成像和颅内压 动力学 临床研究小组，将包括一个神经外科负责人 伤害研究员，在MCV接受过头部伤害管理各个方面的培训， 谁将负责协调正在进行的研究， 病人护理 每名临床研究员将被分配一个 三个临床项目，并作为其余两个的备份。 在神经放射学方面的专业知识，用于安排和现场进行成像 程序和技术改进CTCBF，CTCBV和MRI方法将 也由核心提供。 此外，核心将提供访问 到神经外科计算中心进行在线计算机监控， ICU中监测的所有生理参数以及数据 管理专业知识，以分析所有临床项目所必需的数据。

The goal of the clinical investigative core is to accomplish meaningful clinical investigative research while at the same time integrating the highest quality 'state of the art' patient care. The function of the core will be to provide clinical, technical expertise and appropriate facilities to help implement the three clinical protocols of this program project. Many of the tests, investigations, and gathering of data will occur at a time when the patient is the least stable and most care is required. This core centralizes the investigative team which will remain on 24-hour call throughout the year and provide the expertise necessary to carry out the studies involving cerebral microdialysis, cerebral blood flow, magnetic resonance brain water imaging and intracranial pressure dynamics. The clinical research team, will include a neurosurgical head injury fellow, trained at MCV in all aspects of head injury management, who will assume responsibility for coordinating the studies with ongoing patient care. Each clinical research fellow will be assigned one of three clinical projects and serve as back up for the remaining two. Expertise in neuroradiology for scheduling and on-site conduct of imaging procedures, and technical refinement CTCBF, CTCBV, and MRI methods will also be provided by the Core. In addition, the core will provide access to the Neurosurgical computing center for on-line computer monitoring of all physiologic parameters monitored in the ICU as well as data management expertise to analyze data essential to all clinical projects.